This study develops an EPQ model for deteriorating items assuming time and stock dependent demand and time varying holding cost under the effect of inflation in fuzzy environment. Shortages are allowed and partially backlogged. In finding the optimal production quantity, deterioration plays a crucial role in inventory management. Therefore handling of deterioration is in highlight and attracted...

This paper studies uncertainty about the non-linearity of climate change impact. The DIAM 2.3 model is used to compute the sensitivity of optimal CO2 emissions paths with respect to damage function parameters. This builds upon results of the EMF-14 uncertainty subgroup study by explicitly allowing for the possibility of threshold effects and hockey stick damage functions. It also extends to the...

Exposure to X-rays, high-intensity visible light or ultraviolet radiation results in alterations to protein structure such as the breakage of disulfide bonds, the loss of electron density at electron-rich centres and the movement of side chains. These specific changes can be exploited in order to obtain phase information. Here, a case study using insulin to illustrate each step of the radiation...

A postal survey conducted of 172 farms in the intensive farming areas of East and Northeast Scotland revealed that one in four farms considered that there was a serious rabbit {Oryctolagus cuniculus L.) problem. Although a wide range of crops was subject to damage, winter cereals and winter oilseed rape were particularly affected by grazing, especially in the winter and spring periods. Two-thir...

We consider a replacement model for an additive damage process with linear restoration. The replacement policy is of the control limit type. Between replacements the damage level process is modeled as a compound Poisson process with positive jumps and negative drift, re ected at 0. We introduce meaningful cost functionals for this system and determine them explicitly for three special cases whe...

A large number of molecular mechanisms exist to ensure the continued function of perturbed cells. Here we explore a range of mechanisms of molecular robustness. A theory of robustness is proposed in which mechanisms are classified into those that purge damage, and those that buffer damage. The strategy upon which a system settles, is a function of the cost of purgation, and thereby a function o...

The paper discusses valuation issues in the context of climate change impact estimation. Issues addressed are aggregation of damage costs over diverse regions (particularly equity-weighting), differentiation of per-unit values, willingness to pay versus willingness to accept compensation as a basis for valuation, and accountability for impacts. Numerical illustrations show that the damage cost ...

Post-earthquake repair costs are important for evaluating the performance of new bridge design options and different existing bridge configurations in the next major earthquake. Hazard and structural demand models provide information on the probabilistic structural response during earthquakes. Damage and decision models are needed to link the structural response to decisions on bridge repair ac...