CONTEXT The iodothyronine deiodinases D1, D2, and D3 enable tissue-specific adaptation of thyroid hormone levels in response to various conditions, such as hypothyroidism or fasting. The possible expression of D2 mRNA in skeletal muscle is intriguing because this enzyme could play a role in systemic as well as local T3 production. OBJECTIVE We determined D2 activity and D2 mRNA expression in ...

The Godhra-Chhota Udepur (GC) sector (west-central India) is the zone of convergence between two crustal-scale accretion zones, i.e. N/NNE-striking Aravalli Delhi Fold Belt (ADFB) against E-striking Central Indian Tectonic Zone (CITZ). In this study, we demonstrate orogens welded during Early Neoproterozoic. GC sector, recumbently folded basement gneisses, shallow-dipping granitoid mylonites an...

Diabetes results from an inadequate mass of functional β cells, due to either β cell loss caused by autoimmune destruction (type I diabetes) or β cell failure in response to insulin resistance (type II diabetes). Elucidating the mechanisms that regulate β cell mass may be key to developing new techniques that foster β cell regeneration as a cellular therapy to treat diabetes. While previous stu...

STUDY QUESTION Is there a difference in birthweight distribution in ART singletons born after IVF culture in two different culture media? SUMMARY ANSWER There is no effect of culture media on both crude and adjusted birthweight distributions in ART singletons from nulliparous mothers. WHAT IS KNOWN ALREADY Studies on human ART singletons have reported a difference in birthweight in singleto...

A–1 Without loss of generality, assume d1 ≤ d2 ≤ ·· · ≤ d12. If d2 i+2 < d 2 i + d 2 i+1 for some i ≤ 10, then di,di+1,di+2 are the side lengths of an acute triangle, since in this case d2 i < d 2 i+1+d 2 i+2 and d 2 i+1 < d 2 i +d 2 i+2 as well. Thus we may assume d2 i+2 ≥ d2 i + d2 i+1 for all i. But then by induction, d2 i ≥ Fid 1 for all i, where Fi is the i-th Fibonacci number (with F1 = F...

Nonstructural protein 5A protein (NS5A) of hepatitis C virus (HCV) plays an important role in the regulation of viral replication, interferon resistance, and apoptosis. HCV NS5A comprises three domains. Recently the structure of domain 1 has been determined, revealing a structural scaffold with a novel zinc-binding motif and a disulfide bond. At present, the structures of domains 2 and 3 remain...

Malignant mesothelioma (MM) has become a global disease burden for its rising incidence and invariable fatality. D2-40 has been widely used as an immunostaining marker of diagnosing MM, while its diagnostic value has not yet been evaluated. Our study aimed to assess the overall accuracy of D2-40 immunostaining for diagnosing MM through a meta-analysis. A total of 22 studies with 2,264 participa...

Bu çalışmada döndürücüye ait kanat sayısı, sarım açısı ve uzunluğu ile yakıt giriş çapının yanma odasındaki türbülanslı akış yapısı, verimi emisyon değerleri üzerine etkisi araştırılmıştır. Referans alınan döndürücü sayısı (n), (L), (θ) çapı (D2) sırası 10, 40 mm, 45°, 19.5 mm’dir. Kanat (6,8,10,12,14), (0.5L, L, 1.5L, 2L), (30°, 60°, 75°, 90°, 120°) için (0.5 D2, 1.5 2 D2) parametrik değerler ...

Stable isotope labeling is the state of the art technique for in vivo quantification of lymphocyte kinetics in humans. It has been central to a number of seminal studies, particularly in the context of HIV-1 and leukemia. However, there is a significant discrepancy between lymphocyte proliferation rates estimated in different studies. Notably, deuterated (2)H2-glucose (D2-glucose) labeling stud...

The present study investigated the search by correlation dimension (D2) for the effect of six stimuli (sucrose, spearmint, gum-base chewing as a voluntary movement, and three combinations of these stimuli) on EEG findings. Twenty normal adult subjects received sucrose, spearmint oil, gum-base alone, and three combinations of these stimuli. EEG recordings were obtained while the subjects rested ...