Acid hydrolysis revealed the constituent amino acids of brevistin as follows: aspartic acid (D-form 2, L-form 1), L-threonine (1), glycine (1), sum of L-valine and L-isoleucine (1), [L-phenylalanine (1), L-tryptophan (1), and 2, 4-diaminobutyric acid (D-form 1, L-form 1). The constituent fatty acid was elucidated to be anteisononanoic acid by gas chromatography-mass spectrometry. A lactone link...

Linderstrplm-Lang and Ottesen have reported the discovery of a bacterial enzyme which brings about the transformation of ovalbumin to a new, easily crystallizable protein, plakalbumin. Unlike other proteolytic processes, this reaction seems to involve the rupture of a limited number of peptide bonds, with the release of only slightly over 1 per cent of the total ovalbumin nitrogen (1, 2). Ville...

The strain of Escherichia coli K-12 with high aspartase activity was irradiated with UV. After mutagenesis and selection, the mutant B-715 was isolated which was 4-times more active in L-aspartic acid biosynthesis than parental K-12 strain. The highest productivity was achieved while the strain was cultivated in the ammonium fumarate medium in 37 degrees C for 18-30 hours. It was found that bet...

The microbial and enzymatic hydrolysis of poly(aspartic acid) (PAA) has been reviewed. Two PAA-degrading bacteria (Pedobacter sp. KP-2 and Sphingomonas sp. KT-1) were isolated from flesh river water. Pedobacter sp. KP-2 hydrolyzed PAA of high molecular weights over 5000. Sphingomonas sp. KT-1 hydrolyzed only PAA of low molecular weights (<5000), while the cell extract could hydrolyze high-molec...

Vibrational studies of amino acids experimentally and theoretically have been performed. The Semi-empirical methods optimization by PM6 and RM1 on the land d-amino acids (alanine, phenylalanine, aspartic and glutamic acid), showed no difference in energy between l-and d-isomers. The vibrational frequencies were calculated by semi-emprical methods (PM6 and RM1) and ab initio methods (B3LYP/6-31+...

Objective(s) The central nucleus of the amygdala (CeA) is a forebrain structure which is important in regulation of ingestive behavior and there is direct and circumstantial evidence to indicate that some circuits involved with feeding behavior include glutamatergic elements. The present study examined whether administration of NMA (N-Methyl-DL-aspartic acid) or MK801 into the CeA altered wate...

Introduction: Memantine as N-Methyl-D-aspartic acid (NMDA) receptor antagonist is used in some neurological disorders. It has been reported that memantine has modulatory effects on the somatosensory information processing in healthy subjects. This study investigated the effect of memantine on electrophysiological properties of barrel cortex neurons in male rats. Methods: Single unit recording ...