نتایج جستجو برای: cytogenetic investigation

تعداد نتایج: 339100  

Journal: :Journal of chronic diseases 1986
P J Wickramaratne B A Prusoff K R Merikangas M M Weissman

The use of survival time models with non-proportional hazard functions is introduced as a method of studying age of onset effects in family studies. Statistical methods for investigating non-proportionality of the hazard function are described, and the application of these methods is illustrated using data from a family study of depression to investigate transmission of age of onset between pro...

Journal: :Clinical child and family psychology review 2003
Jelani Mandara

The purpose of this paper was to review the theoretical underpinnings, major concepts, and methods of the typological approach. It was argued that the typological approach offers a systematic, empirically rigorous and reliable way to synthesize the nomothetic variable-centered approach with the idiographic case-centered approach. Recent advances in cluster analysis validation make it a promisin...

Journal: :Cancer research 1968
J J van Rood A van Leeuwen A Schippers H Balner

More than 20 different leukocyte or tissue antigens can presently be recognized; they belong to one complex system (HL-A) which is, from the genetic point of view, very similar to the H-2 system in the mouse. Another independent system consisting of two antigens has also been well defined, the Group Five system. The methods of defining these antigens, their tissue distri bution, and complex rel...

Journal: :journal of reproduction and infertility 0

introduction: infertility is a significant multifactorial disorder that can be caused by chromosomal abnormalities. in this study, we aimed to cytogenetically investigate male and female patients admitted to the genetic diagnostic laboratory of kayseri educational hospital in kayseri, turkey with varied clinical prediagnoses of infertility. materials and methods: chromosomes from cultured perip...

Journal: :Ultrasound in Obstetrics and Gynecology 1995

Journal: :journal of sciences islamic republic of iran 0

conventional cytogenetic is the standard technique for detection of philadelphia (ph) chromosome in chronic myeloid leukemia (cml). evaluation of abelson murine leukemia/breakpoint cluster region (abl/bcr) fusion using dual-colour fluorescence in situ hybridization (d-fish) is an alternative approach allowing rapid and reliable detection of the disease. we employed the technique of interphase d...

Journal: :Haematologica 2011
Esperanza Such José Cervera Dolors Costa Francesc Solé Teresa Vallespí Elisa Luño Rosa Collado María J Calasanz Jesús M Hernández-Rivas Juan C Cigudosa Benet Nomdedeu Mar Mallo Felix Carbonell Javier Bueno María T Ardanaz Fernando Ramos Mar Tormo Reyes Sancho-Tello Consuelo del Cañizo Valle Gómez Victor Marco Blanca Xicoy Santiago Bonanad Carmen Pedro Teresa Bernal Guillermo F Sanz

BACKGROUND The prognostic value of cytogenetic findings in chronic myelomonocytic leukemia is unclear. Our purpose was to evaluate the independent prognostic impact of cytogenetic abnormalities in a large series of patients with chronic myelomonocytic leukemia included in the database of the Spanish Registry of Myelodysplastic Syndromes. DESIGN AND METHODS We studied 414 patients with chronic...

Journal: :Cell Death and Differentiation 2004

Journal: :Transactions of the American Ophthalmological Society 2007
James J Augsburger Zélia M Corrêa Nikolaos Trichopoulos

PURPOSE To propose an alternative hypothesis for the observed differential survival of patients with small, medium, and large choroidal melanomas based on recently uncovered cytogenetic evidence about melanocytic choroidal tumors. METHODS Review and analysis of published data. RESULTS Recent evidence has shown that recurring nonrandom cytogenetic abnormalities are present within virtually a...

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