The Cu(I)-catalyzed N,N'-diarylation of natural diamines and polyamines such as putrescine, cadaverine, spermine, spermidine and their homologues is described. Aryl iodides bearing electron-donating and electron-withdrawing groups have been employed in the study. The CuI/2-(isobutyryl)cyclohexanone/DMF catalytic system has found to be more efficient in the diarylation of diamines and spermine w...

The first examples of the directed, boron-mediated aldol reaction between different ketones are presented. Transformation of a variety of ketones to their corresponding boron enolates with Chx2BCl/Et3N, followed by reaction with acceptor ketones in diethyl ether, and oxidation of the resultant boron aldolate (H2O2, MeOH/pH 7 buffer), provided the aldol addition products. The reaction was most f...

Introduction: Diabetes is chronic disease which characterised by defect in insulin secretion and action leading to hyperglycaemia. Aim: To detect protein carbonyl as oxidative stress marker Type 2 Mellitus (T2DM). Materials Methods: The present cross-sectional study was conducted on 100 subjects (aged 40 70 years) out of 50 were T2DM normal individuals. Serum tested for Fasting Blood Sugar (FBS...

In this research, the treatment of cyclohexanone, malononitrile, and aromatic aldehydes was carried out for successful synthesis orthoaminocarbonitrile tetrahydronaphthalenes by using butyl-3-methylimidazolium hexafluorophosphate as a base catalyst. protocol, target products were obtained in high to excellent yields between 85% 95% short reaction times 10 20 min under mild conditions. All ident...