The role of polyprenol sugar derivatives in the biosynthesis of certain eukaryotic glycoproteins has been partly described [ 11. Recently lipid pyrophospho-oligosaccharides, postulated as necessary intermediates to initiate N-glycosylation, were shown, when supplied to microsomes, to be effective donors to proteinic acceptors presenting at least one vacant Asn-X-zk sequence: unfolded forms of p...

The transcriptional regulator PlcR and its cognate cell-cell signalling peptide PapR form a quorum-sensing system that controls the expression of extra-cellular virulence factors in various species of the Bacillus cereus group. PlcR and PapR alleles are clustered into four groups defining four pherotypes. However, the molecular basis for group specificity remains elusive, largely because the bi...

Active eukaryotic RNA polymerase II (RNAP II) was purified by immunoaffinity chromatography, using a monoclonal antibody (mAb) that reacts with the highly conserved heptapeptide repeat of the largest subunit. This mAb (designated 8WG16) was conjugated to CNBr-activated Sepharose and used to purify RNAP II from wheat germ and calf thymus. The subunit composition of the immunoaffinity-purified en...

FSH and luteinizing hormone (LH) are secreted constitutively or in pulses, respectively, from pituitary gonadotropes in many vertebrates, and regulate ovarian function. The molecular basis for this evolutionarily conserved gonadotropin-specific secretion pattern is not understood. Here, we show that the carboxyterminal heptapeptide in LH is a gonadotropin-sorting determinant in vivo that direct...

Numerous cyanobacterial species are capable of producing potent toxins, which have been known to cause intoxications and fatalities in wildlife, livestock and humans. Microcystis is amongst the most ubiquitously distributed blue-green algal genus and almost invariably produces cyclic heptapeptide toxins called microcystins (MC). These toxins are highly persistent in water (several weeks). Highe...

Finite affine groups are given by groups of translations and di- lations on finite cyclic groups. For cyclic groups of prime order we develop a time-scale (wavelet) analysis and show that for a large class of non-zero window signals/vectors, the generated full cyclic wavelet system constitutes a frame whose canonical dual is a cyclic wavelet frame.

experimental study of the cyclic behavior of unsaturated materials is more complex than that of the saturated materials due to the required equipment, experience and time. furthering investigations in the field of unsaturated materials is necessary to better understand its complexity and sensitivity of unsaturated cyclic parameters to different determinants such as suction path, stress path, lo...