نتایج جستجو برای: cyc lophosphamide
تعداد نتایج: 1096 فیلتر نتایج به سال:
BACKGROUND Although most circadian clock components are conserved between Drosophila and mammals, the roles assigned to the CRYPTOCHROME (CRY) proteins are very different: Drosophila CRY functions as a circadian photoreceptor, whereas mammalian CRY proteins (mCRY1 and 2) are transcriptional repressors essential for molecular clock oscillations. RESULTS Here we demonstrate that Drosophila CRY ...
Qualitative spatial reasoning is usually performed using spatial calculi specially designed to represent certain aspects of spatial knowledge. However most calculi must be adapted for use in applications where additional constraints are at play. This paper combines the DRA and CYC algebras into a new calculus for reasoning within network structures. In the process we prove some interesting resu...
CycSecure is a network risk assessment and network monitoring application that relies on knowledge-based artificial intelligence technologies to improve on traditional network vulnerability assessment. CycSecure integrates public reports of software faults from online databases, data gathered automatically from computers on a network and hand-ontologized information about computers and computer...
چکیده فرض کنیم g یک گروه باشد مرکز ساز عنصر x?g را به صورت زیر تعریف می کنیم؛ c_g (x)={y?g? است آبلی?x,y? } اگر در این تعریف، کلمه آبلی را با کلمه دوری جایگزین کنیم. یک زیر مجموعه از مرکزساز به دست می آید که به این زیرمجموعه، دوری ساز x در g می گوییم و آن را با cyc_g (x) نشان می دهیم پس؛ cyc_g (x)={y?g? ?x,y?است دوری} همچنین، cyc(g) را به صورت زیرتعریف می کنیم؛ cyc(g)={x?g??x,y?است دور...
BACKGROUND Broadly expressed transcriptions factors (TFs) control tissue-specific programs of gene expression through interactions with local TF networks. A prime example is the circadian clock: although the conserved TFs CLOCK (CLK) and CYCLE (CYC) control a transcriptional circuit throughout animal bodies, rhythms in behavior and physiology are generated tissue specifically. Yet, how CLK and ...
OBJECTIVE Glomerulonephritis is a severe manifestation of systemic lupus erythematosus (SLE) that is usually treated with an extended course of intravenous (IV) cyclophosphamide (CYC). Given the side effects of this regimen, we evaluated the efficacy and the toxicity of a course of low-dose IV CYC prescribed as a remission-inducing treatment, followed by azathioprine (AZA) as a remission-mainta...
OBJECTIVE Oral cyclophosphamide (CYC) is a promising therapy for Systemic Sclerosis (SSc)-related interstitial lung disease (ILD). The use of intravenous (i.v.) pulses has been considered as an alternative route of drug administration, possibly associated with reduced toxicity. Our objectives were to re-evaluate our experience with i.v. CYC, to review the literature, and to pool our results wit...
A new generation of knowledge/databases is emerging. These systems contain thousands of objects, densely interconnected and heterogeneously organized, entered from many sources, both human and automated. Such systems present tremendous challenges to their users, who must locate relevant information quickly and add new information effectively. Our research aims to understand and support the know...
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