نتایج جستجو برای: cvid
تعداد نتایج: 525 فیلتر نتایج به سال:
common variable immunodeficiency (cvid) is a heterogeneous group of disorders, characterized by hypogammaglobulinemia and increased susceptibility to recurrent infections, autoimmunity and malignancies. we have previously shown that some pediatric patients with cvid can respond to meningococcal polysaccharide vaccine. twelve pediatric cases with cvid were re-evaluated to determine whether bacte...
BACKGROUND Common variable immunodeficiency (CVID) is characterised by hypogammaglobulinaemia and a broad clinical spectrum, mainly showing recurrent bacterial infections accompanied sometimes by increased susceptibility to chronic lung disease, autoimmunity, and neoplastic diseases. OBJECTIVES To evaluate the clinical and immunological characteristics of patients with CVID in Mexico. METHO...
BACKGROUND Children with common variable immunodeficiency (CVID) have increased susceptibility to infections. OBJECTIVE We evaluated the role of intravenous immunoglobulin (IVIG) replacement therapy on the clinical outcome of patients with CVID. METHODS We studied children diagnosed with CVID and treated with IVIG (500 mg/kg every 3 weeks). RESULTS The study population comprised 29 childr...
We report a severe case of diarrhea in a 62-year-old female HIV-negative patient from whom Giardia lamblia and Isospora belli were isolated. Because unusual and opportunistic infections should be considered as criteria for further analysis of immunological status, laboratory investigations led to a diagnosis of common variable immunodeficiency (CVID). This is the first reported case of isospori...
Sir, Common variable immunode¢ciency (CVID), one of the most frequent of the primary speci¢c immunode¢ciencies, is a heterogeneous group of syndromes characterized by a de¢ciency in antibody synthesis associated with panhypogammaglobulinaemia and recurrent bacterial infections (1). The occurrence of non-caseating granulomas in di¡erent organs, including the skin, has been described previously. ...
Common variable immunodeficiency disorders (CVIDs) are the most frequent symptomatic primary immune deficiency condition in adults. The genetic basis for the condition is not known and no single clinical feature or laboratory test can establish the diagnosis; it has been a diagnosis of exclusion. In areas of uncertainty, diagnostic criteria can provide valuable clinical information. Here, we co...
PATIENT Female, 22 FINAL DIAGNOSIS: Pneumococcal meningitis Symptoms: Fever • headache • neck stiffness • nuchal rigidity • photophobia MEDICATION Ceftriaxone Clinical Procedure: - Specialty: Neurology. OBJECTIVE Rare disease. BACKGROUND Common variable immunodeficiency (CVID) is a primary immunodeficiency associated with hypogammaglobulinemia and other various clinical manifestations. It...
BACKGROUND Despite considerable effort, the genetic factors responsible for >90% of the antibody deficiency syndromes IgAD and CVID remain elusive. To produce a functionally diverse antibody repertoire B lymphocytes undergo class switch recombination. This process is initiated by AID-catalyzed deamination of cytidine to uridine in switch region DNA. Subsequently, these residues are recognized b...
common variable immunodeficiency (cvid) is the most common symptomatic primary antibody deficiency, characterized by reduced serum immunoglobulins levels and increased susceptibility to recurrent pyogenic infections. in this study, we evaluated cd40 ligand expression on stimulated versus unstimulated t-helper lymphocytes of nine common variable immunodeficient patients in comparison with fiftee...
Lymphocytic interstitial pneumonia (LIP) is a rare form of interstitial lung disease. A few case reports have described an association with common variable immunodeficiency (CVID). Corticosteroids are usually used to treat symptomatic patients but their efficacy has never been studied in a controlled trial. We describe a patient with LIP and CVID who was treated monthly with intravenous immunog...
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