The high-performance liquid-chromatographic method described here for the quantitative analysis for nitrofurantoin in urine and plasma involves direct analysis of urine samples and analysis of plasma samples after protein precipitation by methanol. The assay, which requires only 0.2 ml of biological fluid and shows a linear relationship in the range 0.02 to 200 mg/liter, can be performed in 9 m...

PURPOSE Tears are a particularly limited body fluid and commonly used in the diagnosis of patients who have ocular diseases. A popular method for analysis of ocular inflammation in tears uses Luminex® bead multiplex technology to generate valuable multiple cytokine profile outputs with 25-50 µl tear sample volume. We propose a method for measuring tear cytokines with 5 μl tear sample volume and...

BACKGROUND The 1st WHO International Reference Reagents (IRRs) for 6 human chorionic gonadotropin (hCG)-related molecular variants, highly purified and calibrated in substance concentrations by the IFCC Working Group for hCG, permit experimental elucidation of what commercially available hCG methods measure in molar terms and enable assessment of their fitness for clinical purposes. METHODS P...

PURPOSE The aim of this study was to establish the reliability of gross efficiency (GE) measurement (the ratio of mechanical power input to metabolic power output, expressed as a percentage) using the Douglas bag method. METHODS The experiment was conducted in two parts. Part 1 examined the potential for errors in the Douglas bag method arising from gas concentration analysis, bag residual vo...

We consider the problem of estimating the distribution of the expected utility of the Bayesian model (expected utility is also known as generalization error). We use the cross-validation predictive densities to compute the expected utilities. We demonstrate that in flexible non-linear models having many parameters, the importance sampling approximated leave-one-out cross-validation (IS-LOO-CV) ...

Currently: Associate Professor at Chalmers/GU (substitute, until 2007-06-01). 050110-060110: Substitute in mathematics at Sigrid Rudebecks gymnasium (an independent school in Gbg). 020901-050110: Teaching students at Chalmers/GU (Guest teacher, i.e. not a permanent appointment) in different courses in mathematics. 990701-020901: PhD-student at Växjö University (VXU). 95-990701: Under graduate a...

This report describes a system in which a population of agents develops a set of syllables for imitating each other. Initially, the agents do not have a repertoire of sounds. However, they are able to produce a range of human like syllables that consist of an onset (consonant) and a nucleus (vowel). Through a pressure to imitate each other successfully and a pressure to increase the number of s...