BACKGROUND We explored the value of admission levels of N-terminal pro-brain natriuretic peptide (NTProBNP) that best predicts poor myocardial tissue perfusion following primary percutaneous coronary intervention (PPCI) in patients admitted with acute ST-segment-elevation myocardial infarction (STEMI). METHODS We enrolled 90 consecutive patients admitted with acute STEMI who underwent PPCI an...

BACKGROUND Proliferative markers are not recommended as prognostic factors for clinical use in breast cancer due to lack of standardization in methodology. However, proliferation is driving several gene expression signatures emphasizing the need for a reliable proliferative marker for clinical use. Studies suggest that cyclin A is a prognostic marker with satisfying reproducibility. We investig...

A new method recently used for measuring the temperature is using tympanic thermometer. The aim of this study was to compare the accuracy of this method with rectal and axillary measurement in children less than 6 years old. A total of 220 pair ears, axillaries, and rectal sites were used to determine the body temperature in patients aged between 3 months to 6 years who referred to Emergency De...

KRASG12C mutations occur in ~14% of NSCLC adenocarcinomas. Adagrasib (ada), a inhibitor, was selected for favorable properties, including long half-life (23 h), dose-dependent pharmacokinetics, and central nervous system penetration. In the KRYSTAL-1 registrational phase II Cohort A, ada showed clinical activity with manageable tolerability patients (pts) previously treated KRASG12C-mutated NSC...

Soit P une matrice bistochastique de taille n, et Π permutation n. Dans cet article, nous intéressons au temps mélange la chaîne Markov dont transition est donnée par Q=PΠ. En d’autres termes, alterne entre des sauts aléatoires gouvernés déterministes Π. Nous montrons que si choisie uniformément hasard, alors, sous légères hypothèses sur P, avec grande probabilité, Q présente un cutoff logn h, ...

a standard breakfast was evaluated as a screening test (bt) for gestational diabetes in a case-control study. blood sugar (bs) was measured 1 hour after a breakfast that had 50gr simple sugar and was designed based on women preferences. in the same women glucose challenge test (gct, 50gr 1hour glucose screening test) was performed one week later in randomized sequential. cutoff values for both ...

PURPOSE Although stereotactic ablative body radiotherapy (SABR) is widely used therapeutic technique, predictive factors of radiation pneumonitis (RP) after SABR remain undefined. We aimed to investigate the predictive factors affecting RP in patients with primary or metastatic lung tumors who received SABR. MATERIALS AND METHODS From 2012 to 2015, we reviewed 59 patients with 72 primary or m...

PURPOSE To develop normal tissue complication probability (NTCP) model with least absolute shrinkage and selection operator (LASSO) to analyze dose-volume effects that influence the incidence of acute diarrhea among gynecological patients with/without prior abdominal surgery. METHODS AND MATERIALS Ninety-five patients receiving gynecologic radiotherapy (RT) were enrolled. The endpoint was def...