OBJECTIVE To describe ocular findings in 2 patients with disseminated coccidioidomycosis diagnosed by skin biopsy. METHODS The clinical and histopathologic findings of the 2 patients were reviewed retrospectively. RESULTS One patient had a unilateral, granulomatous iridocyclitis with multiple iris nodules and a large vascularized anterior chamber mass, in the setting of pulmonary, cutaneous...

CASE REPORT A 94-year-old male patient presented with multiple vegetating and granulomatous nodules on the right groin and gluteal region in the recent one year (Fig. 1A). He was robust before without any other systemic diseases except oral erosion developed one week before he visited our clinic. Tentative diagnosis included cutaneous fungal infection, cutaneous T cell lymphoma, and vegetating ...

Ataxia-telangiectasia (A-T) is a complex multisystem disorder characterized by progressive neurological impairment, variable immunodeficiency and oculo-cutaneous telangiectasia. A-T is a member of chromosomal breakage syndromes and it is caused by a mutation in the ataxia-telangiectasia mutated (ATM) gene. Because of a wide clinical heterogeneity, A-T is often difficult to diagnose in children....

Introduction: Sarcoidosis is a systemic non-infectious granulomatous disorder which exhibits various specific and non-specific cutaneous manifestations. Erythema nodosum-like eruption is a rare specific lesion associated with sarcoidosis, which histologically shows noncaseating epithelioid granuloma. It is suggested that this type is frequently associated with ocular sarcoidosis. Main observati...

Leishmaniasis is a parasitic disease caused by Leishmania species and is classified into three forms; cutaneous, mucocutaneous, and visceral. The eyelid is a rare site involved by leishmaniasis and only makes up 2.5% of cases with cutaneous leishmaniasis (CL). Although CL can affect both upper and lower lids on either their outer or inner aspects, the lateral canthus is most often affected. The...

Cutaneous leishmaniasis (CL), an uncommon disorder in South-East Asia, including Bangladesh, often presents as granulomatous plaque on the exposed areas, with a high index of suspicion required for diagnosis. Here we report the first imported case of CL caused by Leishmania tropica in a migrant Bangladeshi worker in the Kingdom of Saudi Arabia (KSA). The case, initially suspected as a case of c...

Opportunist acid-fast bacilli sometimes cause progressive indolent infections of the skin, producing nodules, granulomatous lesions, abscesses, or ulcers. Some of these mycobacteria prefer temperatures lower than 370C for growth, and minor trauma or devitalized tissue probably aid their entry and establishment. One such organism, Mycobacterium marinum (balnei), was identified as the cause of ep...

A 46-year-old woman with a history of dasatinib-resistant chronic myeloid leukaemia, clonal evolution and monosomy 7 underwent reduced intensity conditioned in vivo T-cell-depleted allogeneic haematopoietic stem cell transplantation (HSCT) from a matched unrelated donor. Following the transplantation, she developed recurrent cutaneous graft versus host disease (GvHD), which required treatment w...

Sarcoidosis is a multiorgan granulomatous disease in which the skin is one of the frequently involved target organs. Cutaneous involvement occurs in a third of patients with sarcoidosis and has protean manifestations. More than a century has passed since the initial description of sarcoidosis, but its cause continues to be an enigma. Recent studies have introduced several new insights into the ...