BACKGROUND The aim of this clinical trial was to assess the efficacy and safety of curcuminoid complex extract from turmeric rhizome with turmeric volatile oil (CuraMed®) and its combination with boswellic acid extract from Indian frankincense root (Curamin®) vs placebo for the treatment of 40- to 70-year-old patients with osteoarthritis (OA). METHODS The effects of CuraMed® 500-mg capsules (...

We have previously reported that curcumin analogs with a C7 linker bearing a C4-C5 olefinic linker with a single keto group at C3 (enone linker) display midnanomolar activity against the bloodstream form of Trypanosoma brucei. However, no clear indication of their mechanism of action or superior antiparasitic activity relative to analogswith the original di-ketone curcumin linker was apparent. ...

BACKGROUND Curcuma longa L. is a well-known medicinal plant that has been used for its anti-cancer, neuroprotective, and hepatoprotective effects. However, the neuroprotective effect of fermented C. longa (FCL) has not been reported. Therefore, in this study, the effectiveness of FCL for the regulation of memory dysfunction was investigated in two brain cell lines (rat glioma C6 and murine micr...

Members of the Zingiberaceae such as turmeric (Curcuma longa L.) and ginger (Zingiber officinale Rosc.) and fenugreek accumulate at high levels in their rhizomes important pharmacologically active metabolites that appear to be derived from the phenylpropanoid pathway. The major constituens of these spices are in ginger, the gingerols, in turmeric these are the curcuminoids and in fenugreek 5, 7...

Several recent clinical studies have demonstrated a positive effect of turmeric/curcumin on a variety of medical conditions. Curcumin supplementation improved artery endothelial function and reduced oxidative stress, which is associated with cardiovascular disease, in healthy middle-aged and older adults.5 Curcumin also demonstrated anti-inflammatory activity by significant reduction of serum a...

INTRODUCTION Tumeric is a spice that comes from the root Curcuma longa, a member of the ginger family, Zingaberaceae. In Ayurveda (Indian traditional medicine), tumeric has been used for its medicinal properties for various indications and through different routes of administration, including topically, orally, and by inhalation. Curcuminoids are components of tumeric, which include mainly curc...

Die Isolierung von Curcuminoiden aus Kurkuma (Curcuma longa L.) wurde durch verschiedene Extraktionsmethoden und Lösungsmittel durchgeführt. erhaltenen Extrakte wurden mittels HPLC auf den Gehalt an Curcumin, Demethoxycurcumin Bisdemethoxycurcumin analysiert. Darüber hinaus das Einfangen freier Radikale die antibakterielle Aktivität der ermittelt. Ergebnisse zeigen, dass höchste Ertrag des Extr...