In the present study, toxicity was developed by oral administration of AFB1 at a dose of (2μg/kg body weight) for 45 days in male mice. Curcuma longa (100 and 200 mg/kg body weight) and Curcumin (50 and 100 mg/kg body weight) were given individually and in combination with AFB1 for 45 days. At the end of 45 days, the blood samples were collected from various groups by heart puncture in eppendro...

Curcuma longa L. (Turmeric), of the family Zingiberaceae, is one of the economically as well as medicinally important plant species. It is a sterile, polyploid and vegetatively propagated spice crop cultivated usually in Southeast Asia. In the current study, we carried out re-sequencing through transcriptome profiling of Curcuma longa cv. Kedaram (Cl_Ked_6). We acquired a total of 1 GB raw data...

The present study aim to evaluate the potential inhibitory effect of Curcuma longa (turmeric) oil on lipophilic, yeast like fungus Malassezia furfur which causes Pityriasis versicolor disease, a common superficial fungal skin disease. The antifungal activity of turmeric oil was screened by using disc diffusion method and microdilution method. Results indicated that, in screening of turmeric oil...

Curcuma zedoaria belonging to the family Zingiberaceae has been used in the traditional system of medicine in India and Southwest Asia in treating many human ailments and is found to possess many biological activities. The rationale of the present study was to isolate, identify, and characterize antitumour principles from the rhizomes of Curcuma zedoaria, to assess its cytotoxic effects on huma...

Typhoid fever is a disease caused by Salmonella Typhi and commonly treated by an antimicrobial agent such as cotrimoxazole. On the other hand, herbal usage has risen as an adjunctive therapy to treat many diseases. Curcuma (Curcuma domestica) is a commonly used herb which consists of curcumin as its major active compound. Curcumin has been known for its antimicrobial effect, but there is no pro...

Curcumin, the active molecule present in Curcuma longa is known for its antitumour, antioxidant, antiarthritic, anti-amyloid, anti-ischemic, anti-inflammatory activities. In addition, it may also be effective in treating malaria, prevention of cervical cancer, etc. High-performance thin-layer chromatography (HPTLC) method has been employed for determination of curcumin in four varieties of turm...

The objective of the study was to determine the effect of role of combination of extracts of Curcuma zedoaria and Aloe vera in reducing melanin synthesis. Yarying concentrations of the extracts of the plan ts were tested for melanogenesis and tyrosinase activity in murine melanoma cells. Extract combinations at a concentrati on of 1-5μ1 showed 50J 50% reduction in melanogenesis without altering...