Several metabolic enzymes assemble into distinct intracellular structures in prokaryotes and eukaryotes suggesting an important functional role in cell physiology. The CTP-generating enzyme CTP synthase forms long filamentous structures termed cytoophidia in bacteria, yeast, fruit flies and human cells independent of its catalytic activity. However, the amino acid determinants for protein-prote...

A new measurement has been investigated, called the collision threshold pressure (CTP), meaning the minimal pressure required to initiate vocal fold collision. The purpose was to find a measurement that would be more accurate and less time-consuming to collect than the presently used phonation threshold pressure (PTP). Fourteen amateur singers – six female and eight male – were measured using a...

The drugs in clinical use against African sleeping sickness are toxic, costly, or inefficient. We show that Trypanosoma brucei, which causes this disease, has very low levels of CTP, which are due to a limited capacity for de novo synthesis and the lack of salvage pathways. The CTP synthetase inhibitors 6-diazo-5-oxo-l-norleucine (DON) and alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid...

In the Canadian Traveler Problem (CTP), a traveler seeks a shortest path to a destination through a road network, but unknown to the traveler, some roads may be blocked. This paper studies the Bayesian CTP (BCTP), in which road states are correlated with known prior probabilities and the traveler can infer the states of an unseen road from past observations of other correlated roads. As general...

Computed tomography perfusion (CTP) is an important functional imaging modality in the evaluation of cerebrovascular diseases, particularly in acute stroke and vasospasm. However, the post-processed parametric maps of blood flow tend to be noisy, especially in low-dose CTP, due to the noisy contrast enhancement profile and the oscillatory nature of the results generated by the current computati...

In wireless sensor networks (WSNs), the communication radius of a single sensor node is constrained. Thus, many-to-one and multi-hop routing protocols are designed to relay collected data back to the sink node. One of the challenges handled by present routing protocols is to prevent or reduce traffic congestion, which inevitably causes high packet drop rate, low energy efficiency, and long end-...

Computational tomography perfusion (CTP) is an important functional imaging modality in the evaluation of cerebrovascular diseases, such as stroke and vasospasm. However, the post-processed parametric maps of blood flow tend to be noisy, especially in low-dose CTP, due to the noisy contrast enhancement profile and the oscillatory nature of the results generated by the current computational meth...

Posterior reversible encephalopathy syndrome (PRES) can present with focal neurologic deficits, mimicking a stroke and can often represent a diagnostic challenge when presenting atypically. A high degree of suspicion is required in the clinical setting in order to yield the diagnosis. Cerebral CT perfusion (CTP) is utilized in many institutions as the first line in acute stroke imaging. CTP has...

We consider a scalar field theory in Minkowski spacetime and define a coarse grained Closed Time Path (CTP) effective action by integrating quantum fluctuations of wavelengths shorter than a critical value. We derive an exact CTP renormalization group equation and solve it using a derivative expansion approach. Explicit calculation is performed for the λφ4 theory. We discuss the relevance of th...

The Central Trigger Processor (CTP) is the final stage of the ATLAS first level trigger system which reduces the collision rate of 40 MHz to a Level-1 event rate of 100 kHz. An upgrade of the CTP is currently underway to significantly increase the number of trigger inputs and trigger combinations, allowing additional flexibility for the trigger menu. We present the hardware and FPGA firmware of...