BACKGROUND This review is an update on 'Sympathectomy for neuropathic pain' originally published in Issue 2, 2003. The concept that many neuropathic pain syndromes (traditionally this definition would include complex regional pain syndromes (CRPS)) are "sympathetically maintained pains" has historically led to treatments that interrupt the sympathetic nervous system. Chemical sympathectomies us...

UNLABELLED Dysfunction in the central nervous system is thought to underlie the movement disorders that commonly occur in complex regional pain syndrome (CRPS), with much of the literature focusing on reorganization of the primary motor cortex (M1). Presumed changes in the M1 representation of the CRPS-affected body part have contributed to new CRPS treatments, which are increasingly being inte...

Complex regional pain syndrome (CRPS) is a disorder which has variable clinical manifestations. CRPS type I is characterized by an initiating noxious situation, like a crush or soft tissue injury; or by immobilization, such as a tight cast. CRPS type II is characterized by the existence of a defined nerve damage. Among widespread causative factors soft tissue traumas and fractures had been repo...

OBJECTIVE Complex regional pain syndrome (CRPS) describes a broad spectrum of symptoms that predominantly localize to the extremities. Although limb fracture is one of the most frequently reported triggering events, few large-scale studies have shown the occurrence of and factors associated with CRPS following limb fracture. This study aimed to show the occurrence and identify of those factors....

The clinical diagnosis of Complex Regional Pain Syndrome (CRPS) is a dichotomous (yes/no) categorization necessary for clinical decision-making. However, such dichotomous diagnostic categories do not convey an individual's subtle and temporal gradations in severity of the condition, and have poor statistical power when used as an outcome measure in research. This study evaluated the validity an...

BACKGROUND Complex regional pain syndrome (CRPS) is a debilitating pain syndrome characterized clinically by severe pain along with signs and symptoms of autonomic dysfunction. Presyncope and syncope are common in these patients. The purpose of this study was to investigate the cause of these symptoms in these patients. HYPOTHESIS Patients with CRPS are more prone to presyncope and syncope as...

Complex Regional Pain Syndrome (CRPS) type I and II are as the name indicate complex conditions with unclear pathology and unsolved underlying mechanisms. The main clinical characteristics of CRPS are: spontaneous pain, hyperalgesia, movement disorders with bradykinesia, tremor and dystonia, edema, autonomic and trophic changes in skin and adjacent subcutaneous and muscle tissue. Symptoms and o...

Complex regional pain syndrome (CRPS), formerly known as Sudeck's dystrophy and causalgia, is a disabling and distressing pain syndrome. We here provide a review based on the current literature concerning the epidemiology, etiology, pathophysiology, diagnosis, and therapy of CRPS. CRPS may develop following fractures, limb trauma or lesions of the peripheral or CNS. The clinical picture compris...

Complex regional pain syndrome (CRPS) is outlined as a painful and disabling syndrome accompanied by physical changes within the affected extremity, together with allodynia, edema, and baldness, yet as sudomotor and dilatation dysfunction CRPS has been reported most often in adult population, but it has been reported in pe-diatric population as well. Although several modalities are tried for th...

OBJECTIVE To investigate the predictive value of the sympathetic skin response (SSR) in diagnosing complex regional pain syndrome (CRPS) by comparing three diagnostic modalities-SSR, three-phasic bone scans (TPBS), and thermography. METHODS Thirteen patients with severe limb pain were recruited. Among them, 6 were diagnosed with CRPS according to the proposed revised CRPS clinical diagnostic ...