Natural distribution patterns of boron (B) among leaves within a canopy, among leaflets within a leaf, and within single leaflets were determined for coconut palm (Cocos nucifera L.) and within leaves for paurotis palm [Acoelorrhaphe wrightii (Griseb. & H. Wendl.) Becc.]. Leaf B concentrations did not vary significantly among leaves within the canopy or among leaflets within a single leaf for c...

To better understand whether autoimmunity in Lyn-deficient mice arises from compromised central or peripheral B cell tolerance, we examined BCR signaling properties of wild-type and Lyn-deficient B cells at different stages of development. Wild-type mature follicular B cells were less sensitive to BCR stimulation than were immature transitional stage 1 B cells with regard to BCR-induced calcium...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Kobylińska M, Malak R, Majewska K, Fechner B, Samborski W, Kędzia A. Angle of trunk rotation in children suffering from growth hormone deficiency. Pediatria Polska - Polish Journal Paediatrics. 2023;98(1):30-35. doi:10.5114/polp.2023.126246. APA Kobylińska, M., Malak, R., Majewska, K., Fechner, B., Samborski, W., ...

The transcription factor Krüppel-like factor 2 (KLF2) is critical for normal trafficking of T lymphocytes, but its role in B cells is unclear. We report that B cell-specific KLF2 deficiency leads to decreased expression of the trafficking molecules CD62L and β7-integrin, yet expression of sphingosine-1 phosphate receptor 1 (which is a critical target of KLF2 in T cells) was, unexpectedly, minim...

Background: b-Thalassemia major is a serious medical problem.Growth retardation is commonly seen in poly-transfused b-thalassemia patients. The exact mechanism of short stature in childrenwith thalassemia major is not well understood, however, it isbelieved to be multi-factorial.Objective: To study the growth state and its relationship to growthhormone (GH) deficiency in b-thalassemia patients....

Infants with inherited deficiency of pulmonary surfactant protein (SP) B develop respiratory failure at birth and die without lung transplantation. We examined aspects of surfactant metabolism in lung tissue and lavage fluid acquired at transplantation or postmortem from ten infants born at term with inherited deficiency of SP-B; comparison groups were infants with other forms of chronic lung d...

Inactivation of p53, themaster regulator of cellular stress and damage signals, often allows cells that should die or senesce to live. Loss of Dicer, an RNase III–like enzyme critical in microRNA biogenesis, causes embryonic lethality and activation of the p53 pathway. Several nonhematopoietic cell types that contain inactivated p53 have been shown to surviveDicerdeletion, suggesting that p53 l...

The pharmacological mechanism of drug pair of astragali and cinnamon in shiquan dabu decoction were studied in blood deficiency and Qi deficiency modeled mice. In Qi deficiency, the drug pair of astragali and cinnamon in shiquan dabu decoction had the ability of improving the number of white blood cells and peyer patches, and T cell activity. It had no action in red blood cell number and phagoc...

The regulation of iron (Fe) homeostasis is critical for plant survival. Although the systems responsible for the reduction, uptake, and translocation of Fe have been described, the molecular mechanism by which plants sense Fe status and coordinate the expression of Fe deficiency-responsive genes is largely unknown. Here, we report that two basic helix-loop-helix-type transcription factors, bHLH...