in tropical and subtropical countries, envenomation by scorpions (so-called scorpionism) represents a serious public health problem. in the present study, the toxic effects of mice ld50 injections of mesobuthus eupeus (me) venom on the kidney and liver of anesthetized rabbits were investigated. six rabbits were selected and alt, ast, bun and creatinine were measured at 0, 1 and 3 hours after...

chronic kidney disease (ckd) is a major public health problem that often goes unrecognized until late-stagedisease. patients with chronic kidney disease face with uremic toxins and hyperkalemia. also fluid overloadin ckd patients is associated with rapid decline in kidney function. lactulose is a hyper osmotic agent andas a prebiotic plays an important role in regulating serum urea and potassiu...

background: postoperative cognitive dysfunction (pocd) has been an important complication of cardiac surgery over the years. neurocognitive dysfunction can affect quality of life and lead to social, functional, emotional, and financial problems in the patient’s life. to reduce pocd, we sought to identify the association between cognitive dysfunction and perioperative factors in patients undergo...

background although magnetic resonance spectroscopy (mrs) has been shown as an effective diagnostic tool in distinguishing inflammation from neoplasm in cystic brain lesions, the optimum approach in selecting the portions of lesions in mrs and the possible effects of different times of echoes (tes) remains unknown. objectives to determine the most effective te in diagnosing neoplastic lesions b...

background: immunotherapy is the only specific treatment for scorpion envenomation. in the present study, the protective effects of polyvalent antivenom against histopathological complications in kidneys and marker changes (bun and creatinine) induced by mesobuthus eupeus (me) scorpion venom was investigated in anesthetized rabbits. methods: twenty four rabbits were randomized into four groups:...

Cystatin C is a 13 KD basic protein that is a member of the cystatin superfamily of cysteine protease inhibitors. The cystatin C gene seems to be a house keeping gene, which is compatible with a stable production rate of cystatin C by most cells. This protein is freely filtered through the glomerulus and almost completely reabsorbed and catabolized by proximal tubular cells. Because of the...

OBJECTIVE To describe a systematic approach to finding the underlying cause of an elevated creatinine level. QUALITY OF EVIDENCE This diagnostic approach is based on a synthesis of information from reference works on nephrology, articles found through a MEDLINE search, and the author's personal experience. MAIN MESSAGE Elevated creatinine levels suggest the differential diagnosis of renal f...

Two forms of radiolabeled creatinine were used in this study, [carbonyl-14C]- and [amidino-14C]creatinine, the latter being synthesized in this laboratory. These labeled compounds were given intravenously to rabbits. Specimens of plasma, urine, feces, and selected tissues were collected. These were liquid-chromatographed and the separated components compared for radioactivity and identity. This...

Correlation between fatty acids intake, serum lipid and lipoproteins with serum creatinine and kidney function in patients with renal failure has been suggested by other investigators. This relationship has not been reported for all types of fatty acids. This study was conducted to determine the association of the consumption of different type of fatty acids, serum lipids and lipoproteins with ...

Objective: Measurement of glomerular filtration rate (GFR) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. As extremely accurate methods of GFR measurement (i.e. Inulin clearance) are expensive and Time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the GFR measurement. Here we have ...