BACKGROUND The Kidney Disease: Improving Global Outcomes (KDIGO) system for classification of acute kidney injury (AKI) severity utilizes a staging schema based on relative changes in serum creatinine (sCr) concentration and urine output. This study compares the in-hospital mortality associated with KDIGO-defined AKI stages and AKI stages defined by absolute sCr increases ('Delta-Creatinine'). ...

objective(s): lupus nephritis (ln) is the main cause of mortality and disability in systemic lupus erythematosus (sle) patients. therefore, utilizing a reliable and non-invasive method for serial measurements of renal function seems to be necessary. the aim of this study was to evaluate the role of urinary lipocalin-2 as a biomarker of renal involvement in sle patients.   materials and methods:...

background when using brain dead donors for organ donation, assessment of kidney function before the procedure is essential. objectives it would be ideal to find an early marker of viability of donor kidneys that is more accurate than creatinine. patients and methods the present study was conducted from march of 2011 to march of 2012, included 52 deceased donors. serum and urinary neutrophil ge...

Background: Accurate and rapid assessment of allograft function is essential in renal transplant recipients in order to detect allograft rejection and to monitor drug nephrotoxicity. We aimed to evaluate the usefulness of cystatin C as a marker of kidney allograft function in the early post-transplant period and to compare this value with that of conventional serum creatinine concentration. Met...

objective: level of serum homocysteine is remarkably common among patients with moderate to sever renal failure. we assessed whether serum homocysteine concentrations were correlated with proteinuria in overt diabetic nephropathy. materials and methods: a cross-sectional study was carried out on 45 patients (29 males, 16 females) with overt proteinuria. all subjects had type 2 diabetes. data in...

the present work compared the clinical efficacy of ropically applied vitamin d3 (cholecalciferol), i a, 25 dihydroxy vitamin d3 (cakitriol) with calcipotriol (dovonex} in the treatment of plaque psoriasis. a randomized, double - blind, left - right, vehicle controlled study to assess the therapeutic efficacy and safety of mice daily application of 1 pg/g and 5 fj.g1g chalecakiferol. 1 pglg calc...