There are many known adipokines differentially secreted from the different adipose depots; however, their paracrine and autocrine effects on de novo adipocyte formation are not fully understood. By developing a coculture method of preadipocytes with primary subcutaneous and visceral adipocytes or tissue explants, we could show that the total secretome inhibited preadipocyte differentiation. Usi...

Let a tuple of n objects obeying a query graph (QG) be called the n-tuple. The “Ddistancevalue” of this n-tuple is the value of a linear function of distances of the n objects that make up this ntuple, according to the edges of the QG. This paper addresses the problem of finding the K n-tuples between n spatial datasets that have the smallest Ddistance-values, the so-called K-Multi-Way Distance...

Objective: Oral health status particularly maxillofacial disorders in adolescents can affect different aspects of the quality of life. This study aimed to assess the age-related quality of life of students in two age groups of 11-14 years and 14-18 years to evaluate its correlation with orthodontic treatment need in adolescents in Isfahan. Methods: This cross-sectional study was conducted on 1...

  Background: Participation is mostly cultural and familial based, and there is not any assessment scales for evaluating kids’ participation in Iranian context, therefore the purpose of this study was developing children’s participation assessment scale for Iranian children.   Methods: Development of this scale occurred in two phases; phase I: planning: following r...

Background: Parental bonding perception leads to the different domains of future life. The goal of this study was to investigate the predictive role of parental bonding perception types of communicational patterns of couples of Tehran. Methods: This research was a correlational and descriptive study. The study sample comprised of 338 individuals who voluntarily participated in the research in ...

Colon cancer is the third most common cancer in the world. The overexpression of tissue factor (TF) in colon cancer cells makes it an ideal target for colon cancer therapy. The purpose of the present study was to develop a TF-targeting energized fusion protein, mlFVII-LDP-AE, which is composed of a mouse Factor VII light chain (mlFVII) as the targeting domain conjugated to the highly cytotoxic ...