BACKGROUND To evaluate the relationships between Reichert Ocular Response Analyzer (ORA) parameters corneal hysteresis (CH) and corneal response factor (CRF) and ocular dimensions, age and intraocular pressure. METHODS Two hundred and twelve eyes of 212 participants with no ocular pathology had CH and CRF measured with the ORA. Intraocular pressure (IOP) was measured with the Dynamic Contour ...

Purpose: To compare and assess the ability of pressure-derived parameters and corneal deformation waveform signal-derived parameters of the ocular response analyzer (ORA) measurement to distinguish between keratoconus and normal eyes, and to develop a combined parameter to optimize the diagnosis of keratoconus. Materials and methods: One hundred and seventy-seven eyes (177 patients) with kerato...

PURPOSE To assess the biomechanical properties of corneas in patients with normal tension glaucoma (NTG) and to compare them with those of patients with primary open-angle glaucoma (POAG), ocular hypertension (OHT), and normal controls (N). METHODS Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann intraocular pressure (IOPg), and corneal compensated IOP (IOPcc) were obtained ...

BACKGROUND To investigate the biomechanical properties of the cornea measured with the Ocular Response Analyzer (ORA) and their association with the anterior segment parameters representing the geometric dimensions including the corneal volume and anterior chamber volume. METHODS A retrospective review of 1020 patients who visited the BGN Eye Clinic was done. The mean radius of the corneal cu...

PURPOSE To determine corneal biomechanical properties in patients with high myopia. DESIGN Observational study. METHODS High myopia patients (n=45, age: 37.0+/-12.6 years) with refractive errors of spherical equivalent (SE) greater than -9.00D were recruited in this study along with healthy subjects (n=90, age: 33.7+/-12.4 years) with refractive errors of SE ranging from 0D to -3.00D. Only ...

Motivated by the discovery of oscillations in tumour necrosis factor-alpha (TNF-alpha) concentration in the aqueous humour of rabbits undergoing corneal allograft rejection, a simple mathematical model is developed for the regulation of TNF-alpha, which incorporates both negative feedback and amplification pathways. Mathematical analysis reveals a surprisingly rich behavioural repertoire for th...

To evaluate corneal hysteresis (CH), acquired with ocular response analyzer (ORA), as a risk factor for glaucoma progression in early-stage primary open-angle (POAG). In historical cohort study, patients diagnosed 2011 POAG according to the Hodapp, Parrish and Anderson classification modified Octopus perimetry followed up until glaucomatous development; otherwise, observations were censored Oct...