نتایج جستجو برای: coq 10

تعداد نتایج: 1018019  

2016
Sylvain Boulmé

Initially promoted by CompCert, the embedding of untrusted Ocaml code into extracted code from Coq – through a skeptical approach – significantly simplifies Coq developments of formally proved software. However, as illustrated by various examples of this paper, such an embedding could be unsound. This paper conjectures sufficient conditions to ensure soundness. And, it illustrates the power of ...

Journal: :Molecules 2016
Alfonso Varela-López Francesca Giampieri Maurizio Battino José L Quiles

Coenzyme Q (CoQ) is a naturally occurring molecule located in the hydrophobic domain of the phospholipid bilayer of all biological membranes. Shortly after being discovered, it was recognized as an essential electron transport chain component in mitochondria where it is particularly abundant. Since then, more additional roles in cell physiology have been reported, including antioxidant, signali...

1997
Samuel Boutin

In this paper we explain how computational reeection can help build eecient certiied decision procedure in reduction systems. We have developped a decision procedure on abelian rings in the Coq system but the approach we describe applies to all reduction systems that allow the deenition of concrete types (or datatypes). We show that computational reeection is more eecient than an LCF-like appro...

1997
Laurent Théry

This paper shows on a non-trivial example that it is possible to mix proving and computing using current technologies. We present a proof of the Buchberger's algorithm that has been developed in the Coq proof assistant. The formulation of the algorithm in Coq can then be eeciently compiled and used to do computation. Preuve et Calcul Formel: une version certiiie de l'algorithme de Buchberger RR...

2018
Sebastian Bohne Christoph Kreitz

We have developed an alternative approach to teaching computer science students how to prove. First, students are taught how to prove theorems with the Coq proof assistant. In a second, more difficult, step students will transfer their acquired skills to the area of textbook proofs. In this article we present a realisation of the second step. Proofs in Coq have a high degree of formality while ...

Journal: :The Biochemical journal 2013
Fernando Gomes Erich B Tahara Cleverson Busso Alicia J Kowaltowski Mario H Barros

Saccharomyces cerevisiae has three distinct inner mitochondrial membrane NADH dehydrogenases mediating the transfer of electrons from NADH to CoQ (coenzyme Q): Nde1p, Nde2p and Ndi1p. The active site of Ndi1p faces the matrix side, whereas the enzymatic activities of Nde1p and Nde2p are restricted to the intermembrane space side, where they are responsible for cytosolic NADH oxidation. In the p...

2016
Bethany J. Jenkins Thomas M. Daly Joanne M. Morrisey Michael W. Mather Akhil B. Vaidya Lawrence W. Bergman

Coenzyme Q (CoQ, ubiquinone) is a central electron carrier in mitochondrial respiration. CoQ is synthesized through multiple steps involving a number of different enzymes. The prevailing view that the CoQ used in respiration exists as a free pool that diffuses throughout the mitochondrial inner membrane bilayer has recently been challenged. In the yeast Saccharomyces cerevisiae, deletion of the...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Danielle C Lohman Farhad Forouhar Emily T Beebe Matthew S Stefely Catherine E Minogue Arne Ulbrich Jonathan A Stefely Shravan Sukumar Marta Luna-Sánchez Adam Jochem Scott Lew Jayaraman Seetharaman Rong Xiao Huang Wang Michael S Westphall Russell L Wrobel John K Everett Julie C Mitchell Luis C López Joshua J Coon Liang Tong David J Pagliarini

Coenzyme Q (CoQ) is an isoprenylated quinone that is essential for cellular respiration and is synthesized in mitochondria by the combined action of at least nine proteins (COQ1-9). Although most COQ proteins are known to catalyze modifications to CoQ precursors, the biochemical role of COQ9 remains unclear. Here, we report that a disease-related COQ9 mutation leads to extensive disruption of t...

Journal: :Journal of Functional Programming 2023

Contemporary proof assistants such as Coq require that recursive functions be terminating and corecursive productive to maintain logical consistency of their type theories, some ensure these properties using syntactic checks. However, being syntactic, they are inherently delicate restrictive, preventing users from easily writing obviously or at whim. Meanwhile, there exist many sized theories p...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بوعلی سینا - دانشکده مهندسی 1392

هزینه های کیفیت (coq) یکی از اجزای مهم سیستم مدیریت جامع کیفیت (tqm) می باشد. هزینه های کیفیت معمولا به صورت مجموع هزینه های عدم انطباق و انطباق محصول با مشخصه های کیفی تعریف می شود. هزینه انطباق صرف پیشگیری از کیفیت ضعیف می شود و هزینه عدم انطباق ناشی از کیفیت ضعیف است، که به دلیل شکست محصول یا خدمات، تحمیل می شود. ارزیابی دقیقِ هزینه های کیفیت به طور اساسی قابلیتِاطمینان بهبود کیفی را تحت تاثیر...

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