Heat therapies such as hyperthermia and thermoablation are very promising approaches in the treatment of cancer. Compared with available hyperthermia modalities, magnetic fluid hyperthermia (MFH) yields better results in uniform heating of the deeply situated tumors. In this approach, fluid consisting of superparamagnetic particles (magnetic fluid) is delivered to the tumor. An alternating (ac)...

Magnetic nanoparticle hyperthermia is an attractive emerging cancer treatment, but the acting microscopic energy deposition mechanisms are not well understood and optimization suffers. We describe several approximate forms for the characteristic time of Néel rotations with varying properties and external influences. We then present stochastic simulations that show agreement between the approxim...

We fabricated self-standing films of cellulose nanocrystals (CNC) and electrospun composite fibers with CNC and polyvinyl alcohol both with magnetic properties arising from cobalt iron oxide nanoparticles in the CNC matrix. Aqueous dispersions of cobalt-iron oxide nanoparticles (10–80 nm diameter) and CNCs (ca. 150 nm length) were used as precursor systems for the films and composite fibers. Th...

Recent advances in nanomaterials science contributed to develop new micro- and nano-devices as potential diagnostic and therapeutic tools in the field of oncology. The synthesis of superparamagnetic nanoparticles (SPMNPs) has been intensively studied, and the use of these particles in magnetic hyperthermia therapy has demonstrated successes in treatment of cancer. However, some physical limitat...

Magnetic nanoparticles that are currently explored for various biomedical applications exhibit a high propensity to minimize total surface energy through aggregation. This study introduces a unique, thermoresponsive nanocomposite design demonstrating substantial colloidal stability of superparamagnetic Fe3O4 nanoparticles (SPIONs) due to a surface-immobilized lipid layer. Lipid coating was acco...

Magneto-fluorescent nanocomposites of Zn doped ferrites nanoparticles with Pt complexes for magnetic hyperthermia and fluorescent imaging.

Hydrophobically modified maghemite (γ-Fe(2)O(3)) nanoparticles were encapsulated within the membrane of poly(trimethylene carbonate)-b-poly(l-glutamic acid) (PTMC-b-PGA) block copolymer vesicles using a nanoprecipitation process. This formation method gives simple access to highly magnetic nanoparticles (MNPs) (loaded up to 70 wt %) together with good control over the vesicles size (100-400 nm)...

Drug-Loaded Mucoadhesive Patch In article number 2100203, Sukho Park and co-workers demostrate a drug-loaded patch equipped in wireless capsule, which is delivered to the gastrointestinal tract rapidly accurately by an external magnetic field. The has excellent mucoadhesive properties even wet environment. Since nanoparticles doxorubicin are also loaded patch, it generates heat under alternatin...

concurrent hyperthermia and radiation therapy in treatment of cancer show a strong evidence of a synergistic enhancement. we designed a new self-regulating thermo-brachytherapy seed, which serves as a source of both radiation and heat for concurrent administration of brachytherapy and hyperthermia. the thermo-brachytherapy seed has a core of ferromagnetic material which produces heat when subje...