It has been suggested that copper ion is involved in the pathogenesis of various diseases. The aim of this study is to examine the association of serum copper levels and glycemic control in patients with type 2 diabetes. We recruited a total of 132 patients with type 2 diabetes, and measured their serum copper levels by atomic absorption spectrometry. Serum copper levels were positively correla...

Static secondary ion mass spectrometry was used to study the corrosion inhibitor Irgamet®39 on the surface of copper treated in insulating oils and the effect of temperature changes, by means of temperature programmed desorption experiments under vacuum, on metal coverage. Four commercial oils, both corrosive and noncorrosive, showed no significant influence on the stability of the tolyltriazol...

We have found that copper(II) compounds containing a peptide group in the chelate exhibit high activity for modification or degradation of albumin in the presence of hydrogen peroxide, whereas no activity was detected for the copper(II) compounds without an amide-group. It is suggested that presence of the amide-group in the ligand may play an important role in the formation of a peroxide adduc...

The importance of copper as an essential element can be estimated by the wide range of copper proteins and enzymes playing different roles in biological systems. In the last decades many bioinorganic studies were developed on mimetic complexes of copper-dependent proteins, in order to verify the interrelations between structural and functional properties of active copper centers. Among the most...

Copper is one of the metals described to bind the Parkinson disease-related protein α-synuclein (aSyn), and to promote its aggregation. Although histidine at position 50 in the aSyn sequence is one of the most studied copper-anchoring sites, its precise role in copper binding and aSyn aggregation is still unclear. Previous studies suggested that this residue does not significantly affect copper...

introduction: a major concern of human being is accumulation and toxicity of heavy metals in their body. copper is a heavy metal ion that in concentration of 2 mg/l can cause numerous complications. different treatment methods have been proposed for removing metals from contaminated water by researchers. among these methods, sorption seems a better method with high removal efficiency. in this s...

Wilson disease is an autosomal recessive disorder of copper metabolism. The Wilson disease protein is a putative copper-transporting P-type ATPase, ATP7B, whose malfunction results in the toxic accumulation of copper in the liver and brain, causing the hepatic and/or neurological symptoms accompanying this disease. The cytosolic N-terminal domain (approximately 70 kDa) of this ATPase comprises ...

Powder neutron diffraction reveals that anomalies in electrical-transport properties of Cu 2 ZnGeSe 4 are associated with disordering copper and zinc cations, which is accompanied by a partial melting the copper-ion sub-lattice.

OBJECTIVES The aims of this study were to quantify the metallic ions released by various dental alloys subjected to a continuous flow of saliva and to estimate the nutritional and toxicological implications of such a release. METHODS Four pieces of three nickel-based, one noble, one high-noble and two copper-aluminum alloys were cast and then immersed in a continuous flow of artificial saliva...

Inert gas ion impacts can be used to manipulate atomic assembly processes during the growth of metallic superlattices but the detailed mechanisms are not well understood. Molecular dynamics simulations are used to investigate the effects of ion incident angle and fluence upon the reassembly and structure of a copper surface partially covered with cobalt asperities. In the low ion energy regime,...