To the Editor: Adaptive support ventilation (ASV) allows clinicians to set a maximum plateau pressure (PP) and a desired minute ventilation. Thus, ASV automatically determines the respiratory rate and tidal volume (VT) based on its algorithms and hereto adjusts VT to keep PP below the set maximum. In a lung model with varying mechanics, all mimicking acute respiratory distress syndrome (ARDS), ...

We present three patients with respiratory failure in whom conventional mechanical lung ventilation resulted in unacceptably high levels of carbon dioxide, severe acidosis and high vasopressor requirements. A pumpless arteriovenous extracorporeal carbon dioxide removal device (Novalung) was inserted. Arterial carbon dioxide levels were reduced rapidly with a corresponding increase in pH, reduct...

OBJECTIVE To review the use of airway pressure release ventilation (APRV) in the treatment of acute lung injury/acute respiratory distress syndrome. DATA SOURCE Published animal studies, human studies, and review articles of APRV. DATA SUMMARY APRV has been successfully used in neonatal, pediatric, and adult forms of respiratory failure. Experimental and clinical use of APRV has been shown ...

Background: To determine whether using mechanical ventilation in neonatal intensive care unit (NICU) influences motor development of low birth weight (LBW) infants and to compare their motor development with normal birth weight (NBW) infants at the age of 8 to 12 months using Peabody Developmental Motor Scale 2 (PDMS-2). Methods: This cross sectional study was conducted on 70 LBW infants in ...

998 April 2014 A HEALTHY 26-yr-old with singed nares, carbonaceous tracheal secretions, and respiratory distress was intubated following a house fire. Bronchoscopy (fig.) revealed soot throughout the tracheobronchial tree consistent with severe inhalational injury. Despite ARDSNet goal-directed conventional mechanical ventilation, adequate muscle relaxation, and aerosolized pharmacotherapy of a...