Purpose The National Cancer Institute (NCI) supports a Cancer Centers Program (CCP) including 66 NCI-designated cancer centers. Several CCPs have associations with Integrative Medicine Programs (IMPs). However, limited information is available regarding cancer-CAM research and collaborations between them. An inventory by NCI’s Office of Cancer Complementary and Alternative Medicine (OCCAM) was ...

Statistical process control (SPC) charts are commonly used to monitor quality characteristics in manufacturing processes. When monitoring two or more related simultaneously, multivariate T2 often employed. Like univariate charts, chart pattern recognition (CCPR) plays a crucial role SPC. The presence of non-random patterns indicates that is influenced by one assignable causes and corrective act...

Fragmenting clearing across multiple central counter-parties (CCPs) is costly. This because dealers providing liquidity globally, cannot net trades cleared in different CCPs and this increases their collateral costs. These costs are then passed on to clients through price distortions which take the form of a differential (basis) when same products CCPs. Using proprietary data, we document an ec...

The serum proteins factor H (FH), consisting of 20 complement control protein modules (CCPs), and its splice product FH-like protein 1 (FHL-1; consisting of CCPs 1-7) are major regulators of the alternative pathway (AP) of complement activation. The engineered version of FH, miniFH, contains only the N- and C-terminal portions of FH linked by an optimized peptide and shows ∼ 10-fold higher ex v...

Spontaneous activation enables the complement system to respond very rapidly to diverse threats. This activation is efficiently suppressed by complement factor H (CFH) on self-surfaces but not on foreign surfaces. The surface selectivity of CFH, a soluble protein containing 20 complement-control protein modules (CCPs 1-20), may be compromised by disease-linked mutations. However, which of the s...

External management consultants have been increasingly employed by owners of complex construction projects (CCPs) to foster innovation and improve their organizational capability. However, the dynamics owner-consultant collaboration process in such are still unknown. To bridge this gap, paper explores roles external consultant involvement fostering developing an capability CCPs. Based on survey...

Clathrin-mediated endocytosis has long been viewed as a process driven by core endocytic proteins, with internalized cargo proteins being passive. In contrast, an emerging view suggests that signaling receptor cargo may actively control its fate by regulating the dynamics of clathrin-coated pits (CCPs) that mediate their internalization. Despite its physiological implications, very little is kn...

We studied how predictive microbiology models could practically be applied to HACCP plans with two predictive software programs that are currently available. The software programs were the Food Micromodel elaborated by the Ministry of Agriculture, Fisheries, and Food, U.K. and the Pathogen Modeling Program of Eastern Regional Research Center, U.S. Department of Agriculture. They successfully pr...

In the past few years, there has been an increasing interest in developing project control systems. The primary purpose of such systems is to indicate whether the actual performance is consistent with the baseline and to produce a signal in the case of non-compliance. Recently, researchers have shown an increased interest in monitoring project’s performance indicators, by plotting them on the S...