OBJECTIVE To analyze patterns of central lymph node (LN) metastasis to specific compartments in the neck and predictive factors of contralateral paratracheal LN metastasis in patients who underwent prophylactic bilateral central LN dissection for papillary thyroid cancer (PTC). STUDY DESIGN Prospective study. SETTING Multitertiary centers. SUBJECTS AND METHODS One hundred forty consecutiv...

111In-octreotide scintigraphy in patients with persistent medullary thyroid carcinoma (MTC) visualized tumors in about half of the surgically explored sites. Tumor visualization correlated with rapid tumor growth and large tumor volume as judged from calcitonin levels. The 111In concentration ratio between tumor (T) and blood (B) in surgically excised lymph node metastases of MTC showed a large...

BACKGROUND Various diagnostic modalities have been utilized to aid in the detection of abnormal parathyroid tissue; however, its localization is not always easy. The purpose of this study was to determine whether the evaluation of potential hemodynamic changes in thyroid arteries could aid in the detection of parathyroid adenomas. METHODS Twenty-eight patients with laboratory evidence of hype...

The expression of Fas in thyroid tumours and Graves' disease was analysed by mRNA transcript expression. As compared with unaffected thyroid tissue, Fas expression was enhanced in Graves' disease, adenomas, and papillary and follicular carcinomas. This pattern was also reflected in immunohistochemical studies. The PCR single-strand conformational polymorphism (SSCP) method and DNA sequencing we...

Objective: The purpose of this study is to evaluate the clinicopathologic characteristics and treatment outcomes of Papillary Thyroid Carcinomas (PTC) of the isthmus and to establish an appropriate surgical strategy. Methods: Thirty-four patients with PTC in isthmus are managed by surgery in National Cancer Center/Cancer Hospital of Chinese Academy of Medical Sciences, Peking Union Medical Coll...

1 College of Electric and Information Technology, Hunan University, Changsha, Hunan 410082, China, [email protected] 2 Faculty of Engineering and Applied Science, University of Ontario Institute of Technology, Oshawa, Ontario, Canada L1H 7K4, [email protected] 3 State Key Laboratories of Transducer Technology, Institute of Intelligent Machines, Chinese Academy of Science, Hefei, Anhui 2...