with a diseased person in an adequate manner demands, consequently, the ability to accrue an understanding of this person ' s unique biographical and relational context, in other words, a historical, socio-cultural, and linguistic competence. This demand precludes predefi ned labelling of a person ' s ailment in general and of reports on complex malfunction in particular. However, both clinical...

Social-ecological systems are considered resilient when they are capable of recovering from externally forced shocks. Thus, whether a given system is identified as resilient depends on a number of contested definitions: what constitutes a shock, what constitutes a discrete system, and what constitutes acceptable performance. Here, I present a case study in which outcomes apparent to both the re...

The commercialization of academic research has been promoted by North American policy makers for over 30 years as a means of increasing university financing and to ensure that promising research would eventually find its way to the marketplace. The following issues paper constitutes a reflection on the impact of the Canadian commercialization framework on academic research in the field of genom...

UNLABELLED Long noncoding RNAs (lncRNA) are emerging as major regulators of cellular phenotypes and implicated as oncogenes or tumor suppressors. Here, we report a novel tumor-suppressive locus on human chromosome 15q23 that contains two multiexonic lncRNA genes of 100 kb each: DRAIC (LOC145837) and the recently reported PCAT29. The DRAIC lncRNA was identified from RNA-seq data and is downregul...

[1] The existence of a new route that draws relatively cold waters from the Pacific Ocean to the North Atlantic via the Tasman outflow is presented. The new route materialises with comparable magnitude and characteristics in three independent numerical realisations of the global ocean circulation. Its realism is supported by hydrographic data interpolated via an inverse model. The ‘‘Tasman leak...