Douglas R. White and Michael Houseman For special issue of l’Homme 2013 Regardless of now marriage is locally defined, most people in most places marry (and/or have children with) people who are neither too close (immediate family members) nor overly distant (total strangers). As a result, many members of a given community are linked to each other by multiple direct or indirect ties of consangu...

OBJECTIVE Although numerous studies have found higher rates of abortion and still births following consanguinity (familial marriages), the question of whether consanguinity significantly increases the risk of neonatal death has inadequately been addressed.This study aims to evaluate familial marriage effects on neonatal death in rural areas in Iran. MATERIALS AND METHODS In this nested case-c...

Premarital health examination (PHE) is ideally to prevent sexually-transmitted diseases (STD) within a couple; to detect reproductive problems or hereditary illness which may pass to offspring; and to provide counseling on family planning and genetic health. However, little is known about the implementation of PHE program. We conducted a selfadministered questionnaire survey to participants who...

Spouses' emotional ties to family early in marriage are linked to marital outcomes, but little is known about how these ties affect marital stability and whether these effects vary by race and gender. The present study examines the links between emotional ties to family of origin and in-laws in the first year of marriage and marital stability over the first 16 years of marriage. Data were colle...

Primary immunodeficiencies (PIDs) are a heterogeneous group of genetic disorders caused by defects in the immune system that predispose patients to infections, autoimmune diseases, lymphoproliferation and malignancies. Most PIDs are inherited in an autosomal recessive pattern; therefore, they are more common in areas with high rates of consanguineous marriage. Reports about PIDs from these area...

BACKGROUND Saudi population is unique in that there is a strong preference for cousin marriages in the general population. We studied the prevalence of consanguinity in educated Saudi females and compared the results with the results obtained in their parents, to access if a generation difference in which extensive educational activities have prevailed to inform the people of the influence of c...

In children, sporadic nephrotic syndrome can be related to a genetic cause, but to what extent genetic alterations associate with resistance to immunosuppression is unknown. In this study, we designed a custom array for next-generation sequencing analysis of 19 target genes, reported as possible causes of nephrotic syndrome, in a cohort of 31 children affected by sporadic steroid-resistant neph...

This research aimed to describe the solution model for child marriage. took place in Malang Regency. The subjects this were married couples who at age of children, parents from woman’s side (wife), and community leaders. Research data obtained through observation in-depth interviews, then analyzed with interactive techniques. impact marriage that occured Regency caused family not function prope...

Consanguineous marriages constitute a significant fraction of marriages worldwide and confer a major public health concern on newborns. In addition to the risk of acquiring a recessive genetic disease, the offspring of consanguineous parents are plausibly at an increased risk of preterm birth, decreased anthropometric measurements, congenital defects and mortality. How consanguinity confers suc...