نتایج جستجو برای: connexin 43
تعداد نتایج: 96242 فیلتر نتایج به سال:
In order to examine whether different connexin gene species exert different degrees of tumor-suppressing activity, we characterized growth characteristics of a gap junction-deficient human cancer cell line, HeLa cells, before and after transfection with cDNA for three different connexins, connexin (ex) 26, ex 40, and ex 43. All transfected cell lines (3 clones transfected with the ex 26 gene, 2...
In order to examine whether different connexin gene species exert different degrees of tumor-suppressing activity, we characterized growth characteristics of a gap junction-deficient human cancer cell line, HeLa cells, before and after transfection with cDNA for three different connexins, connexin (ex) 26, ex 40, and ex 43. All transfected cell lines (3 clones transfected with the ex 26 gene, 2...
AIM Gap junction intercellular communication (GJIC) and hemichannel permeability may have important roles during an ischemic insult. Our aim was to evaluate the effect of ischemia on gap junction channels and hemichannels. METHODS We used neonatal rat heart myofibroblasts and simulated ischemia with a HEPES buffer with high potassium, low pH, absence of glucose, and oxygen tension was reduced...
OBJECTIVES We investigated the influence of cardiopulmonary bypass on cardiomyocyte gap junctions and connexins. METHODS Samples were collected at intervals during operation from the right atrial appendage in 21 patients (mean [+/- SD] age 55 +/- 21 years). Immunodetection of connexins was conducted by Western blotting and confocal microscopy with parallel electron microscopic examination of ...
Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal Title: myoblasts with cardiac myocytes in vitro
The present paper analyses the results of competitive blood-cell repopulation experiments in which Cx43-WT (connexin 43 wild-type) host mice, whose own HSCs (haemopoietic stem cells) were deleted, were grafted with fetal liver cells: 50% Gpi-1a (glucose phosphate isomerase-1a)/Cx43-WT cells competing with 50% Gpi-1b/Cx43-WT, 50% Gpi-1b/Cx43-HZ (heterozygous) or 50% Gpi-1b/Cx43-KO (knock-out) ce...
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