Abstract Studies of chronically deafferented participants have illuminated how regaining some motor control after adult-onset loss proprioceptive and touch input depends heavily on cognitive control. In this study we contrasted the performance one such man, IW, with KS, a woman born without any somatosensory fibres. We postulated that her life-long absence proprioception might allowed to automa...

The increase in life expectancy is accompanied by the growing burden of chronic diseases. Hearing loss is perhaps the most prevalent of all chronic diseases. In addition to age-related hearing loss, a substantial number of cases of audiological impairment are either congenital in nature or acquired during childhood. The permanence of hearing loss is mainly due to the inability of the cochlear s...

Zika virus (ZIKV) has recently surged in human populations, causing an increase in congenital and Guillain-Barré syndromes. While sexual transmission and presence of ZIKV in urine, semen, vaginal secretions, and saliva have been established, the origin of persistent virus shedding into biological secretions is not clear. Using a primary adult murine neuronal culture model, we have determined th...

Hereditary sensory and autonomic neuropathy type III (HSAN III) features disturbed proprioception and a marked ataxic gait. We recently showed that joint angle matching error at the knee is positively correlated with the degree of ataxia. Using intraneural microelectrodes, we also documented that these patients lack functional muscle spindle afferents but have preserved large-diameter cutaneous...

objectives: all individuals need to have the ability of appropriate sensory processing for proper functioning in the environment and participation in daily activities. moreover, behavioral functions can be affected by sensory processing problems. this study aimed to determine the relationship between behavioral problems and sensory processing in 7 to 10 years old children with attention deficit...

Sensory cortices undergo crossmodal reorganisation as a consequence of sensory deprivation. Congenital deafness in humans represents a particular case with respect to other types of sensory deprivation, because cortical reorganisation is not only a consequence of auditory deprivation, but also of language-driven mechanisms. Visual crossmodal plasticity has been found in secondary auditory corti...

BACKGROUND Leprosy is an infectious disease affecting skin and peripheral nerves resulting in increased morbidity and physical deformities. Early diagnosis provides opportune treatment and reduces its complications, relying fundamentally on the demonstration of impaired sensation in suggestive cutaneous lesions. The loss of tactile sensitivity in the lesions is preceded by the loss of thermal s...

background: delayed or missed diagnosis of critical and cyanotic congenital heart disease (chd) in asymptomatic newborns may result in significant morbidity and mortality. the aim of this study was to determine the accuracy of pulse oximetry screening  performed on the first day of life for the early detection of critical and cyanotic chd in apparently normal newborns. methods: this cross-secti...

OBJECTIVE: Diabetes mellitus is one of the most common endocrine diseases with micro-vascular complications and is a common cause of polyneuropathy. We studied the effect of enalapril on electrophysiologic criteria and clinical symptoms of patients with type II diabetes and sensory neuropathy. MATERIALS AND METHODS: A double blind study was conducted on 45 Patients with type II diabetes and ne...

objective: diabetes mellitus is one of the most common endocrine diseases with micro-vascular complications and is a common cause of polyneuropathy. we studied the effect of enalapril on electrophysiologic criteria and clinical symptoms of patients with type ii diabetes and sensory neuropathy. materials and methods: a double blind study was conducted on 45 patients with type ii diabetes and neu...