Congenital adrenal hyperplasia was once considered a rare inherited disorder with severe manifestations. Mild congenital adrenal hyperplasia, however, is common, affecting one in 100 to 1,000 persons in the United States and frequently eluding diagnosis. Both classic and nonclassic forms of the disease are caused by deficiencies in the adrenal enzymes that are used to synthesize glucocorticoids...

BACKGROUND AND OBJECTIVES Congenital cytomegalovirus (CMV) is the leading cause of nongenetic deafness in children in the United States and can cause neurodevelopmental impairment in term infants. Limited data exist regarding congenital CMV infections in preterm infants. We aimed to determine the incidence and association with outcomes of congenital CMV in very low birth weight (VLBW) preterm i...

There is no trustworthy estimate of the incidence of congenital heart disease as a whole, still less of tricuspid atresia. Doubtless many infants have died with tricuspid atresia, on whom no post-mortem examination was made, with merely a diagnosis of congenital heart disease or even unrelated diagnoses, since many of them succumb to infections such as pneumonia, meningitis, septicaemia. The fi...

Congenital toxoplasmosis is a risk for fetus both in 'low' and 'high risk' areas. A cost-benefit analysis based on data from a Finnish prospective study (20.3% seropositivity of pregnant mothers and incidence of 2.4/1,000 seronegative pregnancies) and on Finnish cost data was performed to compare the no-screening and screening alternatives for primary toxoplasma infections during pregnancy. A m...

background: in this study, we examined the epidemiological aspects of neonatal mortality due to intrauterine infections with regard to regional characteristics. methods: consolidated report of the ministry of health and social development of the republic of kazakhstan on children deceased during their first 28 days of life due to intrauterine infections (p23 – congenital pneumonia, p35-39 – inf...

Neonatal purpura fulminans is a rare and life threatening disease that can be inherited or acquired in etiology. It manifests as DIC and extensive subcutaneous thrombosis. The condition is often fatal unless there is prompt diagnosis, and judicious therapy. The most important causes of this condition are infections and congenital deficiency of anticoagulant proteins C and S.In the case of PC (p...

OBJECTIVE To discuss the computed tomographic (CT) and clinical findings of those entities that may present as recurrent deep neck infections. PATIENTS AND METHODS Twelve patients with recurrent deep neck infections and CT scans were retrospectively identified since 1990. Their CT scans and medical histories were reviewed. The diagnosis was pathologically confirmed in all cases. RESULTS The...