Tablets containing metoprolol succinate and Compritol®888ATO in the ratio of 1:2 yielded the desired sustained release profile in phosphate buffer pH 6.8 when evaluated using USP type II paddle apparatus and was selected as the optimized formulation. Robustness of optimized formulation was assessed by studying the effect of factors like varying source of metoprolol succinate and Compritol®888AT...

This article presents results of computer simulations of the hydro-mechanical processes in the lymphedematous tissue under stress of a single chamber of sleeve for pneumatic compression. The discussion was focused on parameters of compression as pressures and inflation times to squeeze out the mobile tissue fluid from the edematous tissue. Simulations have predicted that the process of squeezin...

Reducing test data size is one of the major challenges in testing systems-on-a-chip. This problem can be solved by test compaction and/or compression techniques. Having a partially specified or relaxed test set increases the effectiveness of test compaction and compression techniques. In this paper, we propose a novel and efficient test relaxation technique for combinational and full-scan seque...

Mountain height at convergent plate margins is limited by the megathrust shear force, but it remains unclear how this constraint affects topographic evolution and mountain building transition from subduction to collision. Generally, increases during subduction-collision in response crustal thickening or processes like mantle delamination slab breakoff, main parameters controlling much remain po...

Current thinking about the Next Linear Collider (NLC) places a great deal of importance on magnetic beam compression. However, theoretical work has predicted that a large emittance growth may occur during magnetic compression due to coherent synchrotron radiation and the non-inertial space-charge force[1]. Applications such as the NLC cannot tolerate such beam degradation. To verify this predic...

Nine people died of traumatic asphyxia due to an uncontrolled crowd at a community basketball game in New York City in 1991. We reviewed the circumstances, postmortem findings, and the causes of death. The majority of people had petechiae of the conjunctivae and face consistent with chest compression. There were minimal superficial blunt injuries and no fractures or acute intoxications. These d...

The average muscle activation for the major muscles such as rectus femoris (RF) and Gastrocnemius (GN) during running reveals that they need to exert higher muscle force without wearing compression garment. Previous evidences have shown that lower muscle activity at particular phases of gait cycle prolongs activity, reduces fatigue and reduces injury susceptibility. Therefore, it would seem tha...

A 33-year-old man was found 20 Cm upper of the floor, compressed by rubbish container in the elevator in an unusually awkward position. The scene investigation corresponded exactly with the localization of the injuries found in the victim. This is a case of death by thorax compression without other fatal factors in which the force causing the chest compression was distinctly determined by the a...

Force versus distance profiles acquired by atomic force microscopy probe the structure and interactions of polymer brushes. An interpretation utilizing the Derjaguin approximation and assuming local compression of the brush is justified when colloidal probes are utilized. The assumptions underlying this approach are not satisfied for sharp tips, and deviations from this model were reported for ...