A single-layer CPW-fed active patch antenna oscillator at 2.76 GHz is presented. The patch antenna acts both as a resonator and a radiator. Electromagnetic coupling is utilized for providing the appropriate closed-loop positive feedback. The active antenna is built around a commercially available GaAs MMIC on a low-permittivity = 2 33 Duroid 5870 substrate. The measured effective isotropic radi...

In recent years, textile materials have been found in applications in the cosmetics field. A new sector of cosmetic textiles is introduced and several commercial cosmetic textile products are currently available in the market. On contact with human body and skin, cosmetic textiles are designed to transfer an active substance for cosmetic purposes. The principle is achieved by simply imparting t...

A series of synthesized and commercially available compounds were assessed against PI3Kα for in vitro inhibitory activity and the results compared to binding calculated in silico. Using published crystal structures of PI3Kγ and PI3Kδ co-crystallized with inhibitors as a template, docking was able to identify the majority of potent inhibitors from a decoy set of 1000 compounds. On the other hand...

Bromodomains are gaining increasing interest as drug targets. Commercially sourced and de novo synthesized substituted [1,2,4]triazolo[4,3-a]phthalazines are potent inhibitors of both the BET bromodomains such as BRD4 as well as bromodomains outside the BET family such as BRD9, CECR2, and CREBBP. This new series of compounds is the first example of submicromolar inhibitors of bromodomains outsi...

Active Fiber Composites (AFC) manufactured at EMPA with commercially available piezoelectric ceramic fibers have been investigated for their potential use as sensors and emitters in various applications. The AFC elements have been evaluated with methods derived from the characterization of ultrasonic transducers and acoustic emission (AE) sensors. Electrical impedance measurements as a function...

Metalworking fluids (MWF) play a significant role in manufacturing processes, such as machining or forming. Consequently, a high number of MWF with varying chemical composition are commercially available. However, the working mechanisms of the MWF are still object of discussion in science and application. This paper addresses the possible interactions of additives with metal surfaces taking the...

In our continuing study of biologically active natural products from the fruit of Alpinia galanga (Zingiberaceae), we newly isolated three new labdane-type diterpenes, termed galangalditerpenes A-C (1-3), along with four known sesquiterpenes (4-7) and two diterpenes (8 and 9). The stereostructures of 1-3 were elucidated on the basis of their spectroscopic properties. The melanogenesis inhibitor...

We evaluated a commercially available enzyme immunoassay method for determining the concentration of total diazepam plus its active metabolite, nordiazepam, in small amounts of serum and urine. The coefficients of variation were 5% within assay and 8% between assay. Concentrations so measured for patients' sera correlated well with those obtained both by gas chromatography with electron-capture...

Arnica Montana extract, a natural limuloid contains about 59 ingredients out of which sesquiterpene lactones helenalin, and dihydrohelenalin, are considered significant medicinally active ingredients. Arnica Montana is commonly used in folk medicine, CAM, and Homeopathic drug as neurotropic, cardiotropic, Anti-inflammatory, Anti-bacterial, Anti-oxidant, Anti tumors, to control diabetes, etc. Th...

Autostereoscopic 3-D imaging and display system is implemented on the notebook 486 DxII PC with TFT active matrix LCD display module and accompanying lenticular sheet lens. Image processing board (e.g. Targa Plus which is commercially available) is used to capture and display the image. Display experiments for still image and animating graphics image were very promising and satisfactory. Measur...