2, as well as intron 1 and part of intron 2 was amplified by polymerase chain reaction (PCR). Amplification primers were based on the L-ferritin sequence published by Santoro et al4 (GenBank accession no. X03742). DNA fragments were subsequently cloned and more than 10 clones from each patient were sequenced by automated DNA sequencing. Sequence analysis identified a point mutation, C to T, at ...

In the retina of teleost fish, continuous neuronal development occurs at the margin, in the peripheral growth zone (PGZ). We prepared tissue slices from the retina of rainbow trout that include the PGZ and that comprise a time line of retinal development, in which cells at progressive stages of differentiation are present side by side. We studied the changes in dendritic structure and voltage-d...

We present a study of dense gas emission in the Milky Way in order to serve as a basis for comparison with extragalactic results. This study combines new observations of HCN, CS, and CO in individual GMCs and in the Milky Way plane with published studies of emission from these molecules in the inner 500 pc of the Milky Way. We find a strong trend in the fraction of emission from dense gas trace...

INTRODUCTION Recent work has focused on the hair follicle as the main repository of multipotent stem cells in skin, which is a neat model to study the mechanisms regulating the proliferation, migration and final fate of adult stem cells. This review examines the available literature for its location, molecular markers and multipotency. METHODS Peer-reviewed journals and monographs on the subj...

Abstract Deuterium fractionation provides a window into the thermal history of volatiles in solar system and protoplanetary disks. While evidence active molecular deuteration has been observed toward handful disks, it remains unclear whether this chemistry affects composition forming planetesimals due to limited observational constraints on radial vertical distribution deuterated molecules. To ...