The prefrontal cortex (PFC) is among the most evolved brain regions, contributing to our highest order cognitive abilities. It regulates behavior, thought, and emotion using working memory. Many cognitive disorders involve impairments of the PFC. A century of discoveries at Yale Medical School has revealed the neurobiology of PFC cognitive functions, as well as the molecular needs of these circ...

Relatively little is known about the relationship of most personality disorders to executive cognitive functioning despite their associations with frontal cortex activity. Research on genetic influence is lacking for most personality disorders, and research on genetic influences associated with executive cognitive functioning is sparse and mixed. The Florida State Twin Registry was created to c...

Since the seminal publication of Cognitive Therapy and the Emotional Disorders (A. T. Beck, 1976), cognitive therapy has emerged as one of the most popular and widely taught therapeutic modalities of the last 20 years (Rush & Beck, 2000), because, in part, of its consistency with the scientistpractitioner model. Although the scientist-practitioner model has been controversial (Albee, 1970; Barl...

objective: diabetes mellitus (dm) is a common metabolic. one of the unknown complications of dm is cognitive disorders. different types of cognitive impairment caused by dm may affect the quality of life, self-management of diabetes, and glycosylated hemoglobin. this study aimed to determine the prevalence of cognitive impairment and its relationship with glycosylated hemoglobin (hba1c), diabet...

Cognitive neuropsychology has been used successfully in the analysis of adult neuropsychological disorders in both verbal and nonverbal domains. When applied to children, it aims to construct models on the basis of functional lesions manifest within developing systems and provides a theoretical framework within which patterns of intact and deficient skills can be charted over time. These patter...

OBJECTIVE Disorders of executive functions are among the most frequent cognitive deficits, but they remain poorly defined and are subject to heterogeneous assessment. To address this major issue, the Groupe de Réflexion sur l'Evaluation des Fonctions Exécutives (GREFEX) group has proposed criteria for behavioral and cognitive dysexecutive syndromes and has designed a battery including a specifi...

BACKGROUND Alzheimer's disease is a common neurodegenerative disorder in elderly. This study was aimed to systematically evaluate the association between tea intake and the risk of cognitive disorders by meta-analysis. METHODS AND FINDINGS PubMed, Embase and Wanfang databases were systematically searched and a total of 26 observational studies were included in this study. Odds ratios (ORs) an...

objective(s): parkinson's disease (pd) is a progressive neurological disorder associated with motor disabilities and cognitive dysfunction as well. evidence indicates that pd occurs less frequently in women than men, confirming a role for steroid hormones in protection of dopaminergic nigrostriatal neurons. it is reported that soy genistein, an estrogen agonist phytoestrogen, display neuro...