نتایج جستجو برای: codon

تعداد نتایج: 20648  

2016
Hongju Wang Siqing Liu Bo Zhang Wenqiang Wei

Zika virus (ZIKV) is a mosquito-borne virus (arbovirus) in the family Flaviviridae, and the symptoms caused by ZIKV infection in humans include rash, fever, arthralgia, myalgia, asthenia and conjunctivitis. Codon usage bias analysis can reveal much about the molecular evolution and host adaption of ZIKV. To gain insight into the evolutionary characteristics of ZIKV, we performed a comprehensive...

Journal: :Acta biochimica et biophysica Sinica 2005
Hui Lü Wei-Ming Zhao Yan Zheng Hong Wang Mei Qi Xiu-Ping Yu

Chlamydiae are obligate intracellular bacterial pathogens that cause ocular and sexually transmitted diseases, and are associated with cardiovascular diseases. The analysis of codon usage may improve our understanding of the evolution and pathogenesis of Chlamydia and allow reengineering of target genes to improve their expression for gene therapy. Here, we analyzed the codon usage of C. murida...

2017
Julie L. Chaney Aaron Steele Rory Carmichael Anabel Rodriguez Alicia T. Specht Kim Ngo Jun Li Scott J. Emrich Patricia L. Clark

Synonymous rare codons are considered to be sub-optimal for gene expression because they are translated more slowly than common codons. Yet surprisingly, many protein coding sequences include large clusters of synonymous rare codons. Rare codons at the 5' terminus of coding sequences have been shown to increase translational efficiency. Although a general functional role for synonymous rare cod...

Journal: :Intervirology 2009
Ming-Sheng Cai An-Chun Cheng Ming-Shu Wang Li-Chan Zhao De-Kang Zhu Qi-Hui Luo Fei Liu Xiao-Yue Chen

OBJECTIVE The aim was to identify the codon usage bias between the newly identified duck plague virus (DPV) UL35 gene (GenBank accession No. EF643558) and the UL35-like genes of 27 other reference herpesviruses. METHODS A comparative analysis of the codon usage bias of the 28 herpesviruses was performed by using the CodonW 1.4 program and CUSP (create a codon usage table) program of EMBOSS (T...

اسدزاده عقدایی, حمید, بهبودی فرح بخش, فائقه, مقصودی, حسین, ناظم الحسینی مجرد, احسان,

Background: Familial adenomatous polyposis (FAP) is the most common components polyposis syndromes. It incidence is for less than 1 percent of colorectal cancer cases. FAP is characterized by germline mutations in the adenomatous polyposis coli (APC) gene. Generally, there are hundreds to thousands of adenomatous polyps in colon and rectum of patients. The aim of the current study was to evalua...

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