PATIENTS AND METHODS: Clinical and surgical records of 91 patients (29 men, 62 women; mean age 48 years; range 18 to 82 years) with otosclerosis were reviewed following stapedotomy with the small fenestra technique without interposition. The same Teflon-platinum piston was used in all the patients. Audiometric tests were performed within a week before the operation, 5 to 7 days (early evaluatio...

In the mammalian cochlea, acoustic information is carried to the brain by the predominant (95%) large-diameter, myelinated type I afferents, each of which is postsynaptic to a single inner hair cell. The remaining thin, unmyelinated type II afferents extend hundreds of microns along the cochlear duct to contact many outer hair cells. Despite this extensive arbor, type II afferents are weakly ac...

introduction: speech intelligibility, the ability to be understood verbally by listeners, is the gold standard for assessing the effectiveness of cochlear implantation. thus, the goal of this study was to compare the speech intelligibility between normal-hearing and cochlear-implanted children using the persian intelligibility test.   materials and methods: twenty-six cochlear-implanted childre...

objectives: phonemic awareness skills have a significant impact on children speech and language. the purpose of this study was investigating the phonemic awareness skills of children with cochlear implant and normal hearing peers in primary school. methods: phonemic awareness subscales of phonological awareness test were administered to 30 children with cochlear implantation at the first to six...

CONCLUSION Cell transplantation into the utriculus provides an efficient and non-invasive route to introduce embryonic stem (ES) cells into the vestibular and cochlear portions of the inner ear. OBJECTIVE The transfer of stem cells into the inner ear for therapeutic purposes is an important approach to cure damage to the cochlea and vestibulum. A key issue is to provide an entry point for cel...

The aetiology of hearing loss in new-borns in neonatal intensive care is still debated. While the physiopathology of brain, lung and retina damage related to oxygen supplementation has been widely described, no studies have been carried out to define the relationship between hearing loss and supplementation of oxygen in new-borns. In the present investigation, the cochlear morphology of new-bor...

In this thesis different acoustical and electrophysiological approaches for the objective audiological diagnostic are investigated. The utilized methods involve higher stages of the audiometric pathway and therefore allow the assessment of the state of hearing up to neural levels. It was shown that a different method to measure the acoustic reflex elicitation in conjunction with a new robust de...

Age-related hearing loss (ARHL), the progressive loss of hearing associated with aging, is the most common sensory disorder in the elderly population. The pathology of ARHL includes the hair cells of the organ of Corti, stria vascularis, and afferent spiral ganglion neurons as well as the central auditory pathways. Many studies have suggested that the accumulation of mitochondrial DNA damage, t...

Hearing loss is one of the commonest congenital anomalies to affect children world-over. The incidence of congenital hearing loss is more pronounced in developing countries like the Indian sub-continent, especially with the problems of consanguinity. Hearing loss is a double tragedy, as it leads to not only deafness but also language deprivation. However, hearing loss is the only truly remediab...

objectives: this study examined the relationship between working and short-term memory performance, and their effects on cochlear implant outcomes (speech perception and speech production) in cochlear implanted children aged 7-13 years. the study also compared the memory performance of cochlear implanted children with their normal hearing peers. methods: thirty-one cochlear implanted children w...