A nanostructural hydroxyapatite (HA) coating was deposited to the porous Ti6Al4V acetabular cup implants using a room temperature electrophoretic deposition (EPD) process in order to achieve the improved bonding strength between the implants and cells, fast healing, good corrosion resistance and long-term stability after implantation. The micropores created in the coating will improve the bioac...

In this paper, we demonstrate the preparation of silibinin-loaded carbon nanotubes (SWSB) with surface coating agents via non-covalent approach as an effective drug delivery system. The resulting surface-coated SWSB nanocomposites are extensively characterized by Fourier transform infrared (FTIR) and Raman spectroscopies, ultraviolet-visible (UV-Vis) spectrometry and field emission scanning ele...

The purpose of this study is to develop a novel liquisolid technique to enhance the dissolution rate of poorly water soluble drug Carvedilol, a BCS class II drug, which is a β-blocker, by using different excipients. The main components of a liquisolid system are a non volatile solvent, carrier and coating materials and a disintegrant. Liquisolid system refers to the formulations that are formed...

Viscous heating becomes significant in the high speed resin coating process of glass fibers for optical fiber manufacturing. This study focuses on the coating resin flows inside the capillary coating die of optical fiber coating applicator and they are numerically simulated to examine the effects of viscous heating and subsequent temperature increase in coating resin. Resin flows are driven by ...

In general, the evaluation of automotive coatings appearances favors (is considered preferentially) more than chemical and physical properties. Therefore, its improvement is most required. Studying appearance by means of QMS-BP technique, in which it measures some of the most important coating appearance factors, such as: the specular gloss, distinctness of image (DOI) and orange peel. In this ...

In this study, an attempt was made to improve the packing density of calcium phosphate (CaP) coating on a magnesium alloy by tailoring the coating solution for enhanced degradation resistance of the alloy for implant applications. An organic solvent, ethanol, was added to the coating solution to decrease the conductivity of the coating solution so that hydrogen bubble formation/bursting reduces...

in this research, tribological characteristics of ni-p electroless coating and double-layered ni-p/ni-b electroless coating were studied. for this purpose, ni-p electroless coating with 25 μm thickness was initially applied to the surface of steel ck45 samples; then, a double-layered ni-p/ni-b electroless coating, including inner layer of ni-p with 15 μm thickness and outer layer of ni-b with 1...

Coated multiparticulate systems are increasingly popular on the market. Their manufacture in a fluid bed often requires polymer binders. Polymers have been widely studied as inhibitors of crystallization [1]. Migration of drugs into the coating layer has also been described [2] but the influence of the coating polymers on the crystallization of the drug is yet to be studied in more depth. In ou...

BACKGROUND The objective of this study was to evaluate fluid-bed coating as a new technique to prepare a pellet-based solid self-nanoemulsifying drug delivery system (SNEDDS) using cyclosporin A as a model of a poorly water-soluble drug. METHODS The rationale of this technique was to entrap a Liquid SNEDDS in the matrix of the coating material, polyvinylpyrrolidone K30, by fluid-bed coating. ...

Biomimetic calcium phosphate (CaP) coating has been used successfully for protein delivery, but the release of protein from CaP coating is mainly dependent on the limited dissolution of the CaP coating and the passive diffusion of the protein in the CaP coating. In the present work, our aim is to improve the release behavior of protein from CaP coating and make it more controllable. By using bo...