Long-Term Risk in Subjects With White-Coat Hypertension To the Editor: We read with great interest the article by Mancia et al1 clarifying the increased risk of developing sustained hypertension in subjects with white-coat hypertension, compared with normotensive patients, using home blood pressure measurements and ambulatory blood pressure monitoring. This study was performed over a 10-year pe...

This review is concerned with the role of the "extraneous coat" of the ameba in pinocytosis. It also considers the possible role of the extraneous coat as an additional barrier to those exchanges betvw een the cytoplasm and the environment which involve diffusion. Several examples of pinocytosis in mammalian tissues are presented and are appraised with respect to the physical-chemical propertie...

This review is concerned with the role of the "extraneous coat" of the ameba in pinocytosis. It also considers the possible role of the extraneous coat as an additional barrier to those exchanges betvw een the cytoplasm and the environment which involve diffusion. Several examples of pinocytosis in mammalian tissues are presented and are appraised with respect to the physical-chemical propertie...

Trypanosoma brucei survives in mammals by antigenic variation of its surface coat consisting of variant surface glycoprotein (VSG). Trypanosomes change coat mainly by replacing the transcribed VSG genes in an active telomeric expression site by a different VSG gene. There are about 20 different expression sites and trypanosomes can also change coat by switching the site that is active. This rev...

The first step in assembly of the bacteriophage P22 is the formation of a T=7 icosahedral "procapsid," the major components of which are the coat protein and an inner core composed of the scaffolding protein. Although not present in the mature virion, the scaffolding protein is required for procapsid assembly. Eleven amino-acid residues at the extreme carboxyl terminus of the scaffolding protei...

We prospectively evaluated infusion-related toxicities in 82 recipients of autologous bone marrow grafts. The grafts were cryopreserved in 10% dimethylsulfoxide and stored in liquid nitrogen. All grafts were concentrated and buffy-coat cells were collected. Forty-seven grafts were treated ex vivo with 4-hydroperoxycyclophosphamide (4-HC) at 100 micrograms/mL; 26 grafts were further processed us...

This review is concerned with the role of the "extraneous coat" of the ameba in pinocytosis. It also considers the possible role of the extraneous coat as an additional barrier to those exchanges betvw een the cytoplasm and the environment which involve diffusion. Several examples of pinocytosis in mammalian tissues are presented and are appraised with respect to the physical-chemical propertie...

blood transfusion centers are under considerable pressure to produce platelet concentrates with high quality and safety due to the short shelf life of 3-5 days as well as possible bacterial and viral contaminations. for a variety of reasons, many europeans have changed their methods of component production from whole blood using the north american standard platelet-rich plasma method to the buf...