To evaluate whether previously observed associations between parity and cutaneous malignant melanoma (CMM) risk in women reflected a biologic mechanism or resulted from uncontrolled confounding by lifestyle factors associated with parity (e.g., patterns of sun exposure), the authors investigated the effect of reproductive history (parenthood) on CMM risk in both women and men. Using information...

Over the last 10 years CMM has achieved widespread use as a model for improving software organisations. Often CMM is used to standardise software processes across projects. In this paper we discuss this standardisation of SPI in relation to innovation, organisational size and company growth. Our discussion is empirically based on years work and experience working with companies on SPI. In the c...

DOI: This paper reviews the progress of systems biology applied to research on sustainable utilization of Chinese materia medica (CMM) resources in the following aspects: identification and evaluation of CMM resources, analysis of biosynthesis and their regulation of active ingredients in medicinal plants, metabolic engineering and synthetic biology research of medicinal plants, and molecular b...

Pancytopenia is a common haematological condition often encountered in day to day clinical practice. It is defined as a decrease in all the three cell lines of blood viz., red blood cells, leucocytes, and platelets. Many diseases affect production of these cells by bone marrow resulting into pancytopenia i.e., simultaneous presence of anaemia, leucopenia, and thrombocytopenia. Pancytopenia is d...

Rhythm is important in the production of motor sequences such as speech and song. Deficits in rhythm processing have been implicated in human disorders that affect speech and language processing, including stuttering, autism, and dyslexia. Songbirds provide a tractable model for studying the neural underpinnings of rhythm processing due to parallels with humans in neural structures and vocal le...

May 1999 TIS has been actively engaged in process improvement using the Capability Maturity Model for software (software CMM) since the early 1990s and was assessed at Level 3 in 1995. An assessment was performed in 1998 using the CMM-Based Appraisal for Internal Process Improvement (CBAIPI) method [1]. It resulted in a Level 5 rating for TIS, the highest that can be achieved for the software C...

Software testing is still a pain-in-the-neck for many organisations. Because it is only marginally addressed in software process improvement models like CMM, a separate Testing Process Improvement model is needed. The current authors have implemented a structured testing process guided by the “Testing Maturity Model” (TMM). An outline of this model is presented, showing how with growing maturit...

In December 2001 the SEI CMMI Product Team released version 1.1 of the Capability Maturity Model Integrated for Systems Engineering and Software Engineering (CMMI-SE/SW 1.1). After several years of preparation the CMMI replaced both the CMM version 1.1 of 1993 (SW-CMM) and the systems engineering standard EIA 731. According to the SEI survey data, several hundred organisations from all over the...

Clavibacter michiganensis subsp. michiganensis (Cmm) is a Gram-positive seed-transmitted bacterial phytopathogen responsible for substantial economic losses by adversely affecting tomato production worldwide. A high-throughput, cell-based screen was adapted to identify novel small molecule growth inhibitors to serve as leads for future bactericide development. A library of 4,182 compounds known...

OBJECTIVE To assess the use of cervical mucus monitoring (CMM) in women trying to conceive and determine whether monitoring is associated with increased cycle-specific probability of conception (fecundability). DESIGN Time-to-pregnancy cohort study. SETTING Population-based cohort. PATIENT(S) Three hundred thirty-one women trying to conceive, ages 30 to 44 years, without known infertility...