1 CMAP, Ecole polytechnique, CNRS, Université Paris-Saclay, 91128 Palaiseau, France, [email protected] 2 Laboratoire Jean Kuntzmann, CNRS, Université Grenoble-Alpes, BP 53, 38041 Grenoble Cedex 9, France, [email protected] 3 SIMaP, Université Grenoble-Alpes, BP 53, 38041 Grenoble Cedex 9, France, [email protected], [email protected]...

1 CMAP, Ecole polytechnique, CNRS, Université Paris-Saclay, 91128 Palaiseau, France, [email protected] 2 Laboratoire Jean Kuntzmann, CNRS, Université Grenoble-Alpes, BP 53, 38041 Grenoble Cedex 9, France, [email protected] 3 SIMaP, Université Grenoble-Alpes, BP 53, 38041 Grenoble Cedex 9, France, [email protected], [email protected]...

Given an application problem, a hardware-software solution is derived such that the synthesized software , a parallel pseudo-program, can be scheduled and executed on the synthesized hardware, a set of system-level parallel computer speciications, with heuristically optimal performance. This is known as system-level cosynthesis of application-oriented general-purpose parallel systems for which ...

In the framework of Galichon, Henry-Labordère and Touzi [9], we consider the model-free no-arbitrage bound of variance option given the marginal distributions of the underlying asset. We first make some approximations which restrict the computation on a bounded domain. Then we propose a gradient projection algorithm together with a finite difference scheme to approximate the bound. The general ...

OBJECTIVE Our aim was to examine underserved women's perceptions on mobile versus fixed mammography in Santa Clara, California through a focus group study. BACKGROUND  Research has shown that medically underserved women have higher breast cancer mortality rates correlated with under-screening and a disproportional rate of late-stage diagnosis. The Community Health Partnership in Santa Clara C...

Abstract Background Amyotrophic lateral sclerosis (ALS) is a degenerative disease that affects the upper and lower motor neurons. The onset of frequently focal, usually involving distal segments extremities. A dissociated pattern muscle atrophy commonly found in hands feet. This study aims to investigate presence (if any) split indices ALS patients correlate these with confounding factors. tota...

Abstract Background Drug-induced liver injury (DILI) is an adverse reaction caused by the intake of drugs common use that produces damage. The impact DILI estimated to affect around 20 in 100,000 inhabitants worldwide each year. Despite being one main causes failure, pathophysiology and mechanisms are poorly understood. In present study, we developed ensemble learning approach based on differen...

In the connectivity map (CMap) approach to drug repositioning and development, transcriptional signature of disease is constructed by differential gene expression analysis between diseased tissue or cells control. The negative correlation drug, a bioactive compound, assumed indicate its ability “reverse” process. A major limitation traditional CMaP use signatures derived from bulk tissues. Sinc...

Y Y Y Y M H K H T o the Editor: Ischemic peripheral neuropathy is a term used to escribe the neurological deficits of peripheral nerves in patients ith peripheral artery obstructive disease (1). Although ischemic eripheral neuropathy is a major complication of critical limb schemia resulting in impaired quality of life, effective treatment for schemic neuropathy is not available at present. Rec...