A strain of Bacillus licheniformis, established in the digestive tract of gnotobiotic mice, inhibited the subsequent establishment of a Clostridium perfringens strain ingested by the animals. This inhibitory effect depended on the in vivo production by B. licheniformis of an antibiotic substance having a number of the characteristics of bacitracin. If C. perfringens was the first to become esta...

A simple rapid glutamic decarboxylase test is described. This test was found useful in the identification of Escherichia coli, Shigella sp., Providencia alcalifaciens, Clostridium perfringens and Bacteroides fragilis.

Although Clostridium perfringens is recognised as an important cause of clostridial enteric diseases, there is only limited knowledge about the association of particular C. perfringens toxinotypes (types A to E) with mastitis in domestic animals. In this study, mastitis was detected in 213/623 (34.12%) and 8/83 (9.64%) of the quarter milk samples collected from cases of clinical mastitis in cow...

In an effort to explore strategies to control Clostridium perfringens, we investigated the synergistic effect of a ubiquitous bacterial second messenger 3',5'-cyclic diguanylic acid (c-di-GMP) with penicillin G in a broiler challenge model. All chicks were inoculated in the crop by gavage on d 14, 15, and 16 with a mixture of 4 C. perfringens strains. Birds were treated with saline (control gro...

Food-borne diseases constitute a major public health problem. Due to increased morbidity and mortality leading to time loss in the work place and reduced productivity, food-borne diseases across the world cost billions of dollars annually1. The Clostridium group of bacteria is commonly found in soil everywhere in the world, and some of its species live harmlessly in our intestines. Clostridium ...

[This corrects the article on p. 501 in vol. 21.].

Lucena R.B., Farias L., Libardoni F., Vargas A.C. Giaretta P.R. & Barros C.S.L. 2011. Necrotizing enteritis associated with Clostridium perfringens Type B in chinchillas (Chinchilla lanigera). Pesquisa Veterinária Brasileira 31(12):1071-1074. Departamento de Patologia, Universidade Federal de Santa Maria, Camobi, Santa Maria, RS 97105900, Brazil. E-mail: [email protected] Four 3-4 mont...

Clostridium perfringens type D-producing epsilon toxin is a common cause of death in sheep and goats worldwide. Although anti-epsilon toxin serum antibodies have been detected in healthy non-vaccinated sheep, the information regarding naturally acquired antibodies in ruminants is scanty. The objective of the present report was to characterize the development of naturally acquired antibodies aga...

Clostridium perfringens is an important anaerobic pathogen causing food-borne gastrointestinal (GI) diseases in humans and animals. It is thought that C. perfringens food poisoning isolates typically carry the enterotoxin gene (cpe) on their chromosome, while isolates from other GI diseases, such as antibiotic-associated diarrhea, carry cpe on a transferable plasmid. However, food-borne GI dise...

The L-forms of Clostridium perfringens were first reported by Dienes (1950). He described this form as minute, soft, pleomorphic colonies which developed when C. perfringens were grown on penicillin-treated horse serum agar plates. The reversion of L-colonies to bacterial forms has not been reported for C. perfringens. They have been observed in strains of Proteus (Dienes, 1949), Salmonellae (W...