Clonorchis sinensis is a biological carcinogen inducing human cholangiocarcinoma, and clonorchiasis is one of the important endemic infectious diseases in East Asia. The present study investigated survival longevity of C. sinensis adult worms in various in vitro conditions to find the best way of keeping the worms longer. The worms were maintained in 0.85% NaCl, 1×PBS, 1×Locke's solution, RPMI-...

Clonorchiasis sinensis is a food-borne parasitic zoonosis caused by Clonorchis sinensis which infects fish-eating mammals including humans, dogs, cats and pigs. The disease is prevalent in East Asian and Southeast Asian countries. Boott in 1903 first proved the presence of the disease in China. In 1930s doctors from Europe and America,and Japanese carried out the occasional survey in coastal ci...

A large-scale survey was conducted to investigate the infection status of fresh water fishes with Clonorchis sinensis metacercariae (CsMc) in 3 wide regions, which were tentatively divided by latitudinal levels of the Korean peninsula. A total of 4,071 freshwater fishes were collected from 3 regions, i.e., northern (Gangwon-do: 1,543 fish), middle (Chungcheongbuk-do and Gyeongsangbuk-do: 1,167 ...

Opisthorchiasis, together with its associated cholangiocarcinoma, is one of the most important human parasitic diseases on continental Southeast Asia. A great deal of epidemiological data from humans is available on this disease, particularly from the northeast of Thailand, however, only limited information is available on those aspects of the life cycle relating to its Bithynia (Gastropoda) an...

We previously reported the production of monoclonal antibodies (MAbs) to somatic (Billings et aI, 1990) and excretory-secretory (Amornpunt et aI, 1991) antigens of Opisthorchis viverrini. The characteristics of the antigens to which these MAbs reacted are summarized as shown in Table I. It was not surprising to note that all MAbs to the worm metabolic products were directed against the 89-kDa c...

Examination of the original descriptions of genera placed within the family Opisthorchiidae has revealed that only 33 of the original 43 genera are valid members of this family. Further study of these descriptions should also reveal that many of the subfamilies are also invalid. With reference to the original descriptions of these genera, and subsequent literature, a brief survey of the family ...