Clozapine is the second-generation antipsychotic most frequently associated with seizures with risk varying from 1-5%. The seizure types are diverse, varying from generalized tonic-clonic subtype, partial, atonic or myoclonic jerks. Myoclonic and atonic subtypes are more likely to go unrecognized and have been shown to be a harbinger for further seizures of tonic-clonic variety. We report a cas...

UNLABELLED Background Context. Cement leakage is not a rare complication of vertebroplasty, but ascending tonic clonic seizure syndrome is exceptionally rare. We herein report the first case to our knowledge of this complication related to vertebroplasty. Purpose. We herein report the first case of ascending tonic clonic seizure syndrome following epidural cement leakage after percutaneous vert...

To cite: Idris AA, Begum T, Verlage KR, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016215266 DESCRIPTION A 37-year-old Hispanic man with no medical history presented with sudden onset of two episodes of witnessed seizure. On arrival to the emergency room, he experienced another episode of generalised tonic–clonic seizure witnessed by the physician and...

Hemodialysis-associated seizure is a complication of hemodialysis. This report describes the occurrence of seizures in patients with end stage renal disease on dialysis therapy at the Nephrology Institute of Mogi das Cruzes, São Paulo State, Brazil. A retrospective medical history of 189 patients was reviewed to investigate the occurrence of convulsive seizures during dialytic program. Seven pa...

Epileptic seizures are characterized by periods of recurrent, highly synchronized activity that spontaneously terminates, followed by postictal state when neuronal activity is generally depressed. The mechanisms for spontaneous seizure termination and postictal depression remain poorly understood. Using a realistic computational model, we demonstrate that termination of seizure and postictal de...

PURPOSE This study was conducted to evaluate the efficacy and safety of anterior corpus callosotomy with a keyhole approach on refractory seizures and to evaluate this procedure for drop attacks (DAs) and generalized tonic-clonic seizures (GTCSs). METHODS All refractory seizure patients underwent anterior corpus callosotomy (n=31) without other epilepsy surgery. Seizure response and procedure...

OBJECTIVES Scientific interest in potential mobile phone impact on human brain and performance has significantly increased in recent years. The present study was designed to evaluate the effects of mobile phone radiation on seizure threshold in mice. MATERIALS AND METHODS BALB/c male mice were randomly divided into three groups: control, acute, and chronic mobile phone radiation for 30, 60, a...

PURPOSE: Temporal lobectomy is a well-established treatment for refractory temporal lobe epilepsy, yet many patients experience at least one seizure postoperatively. Little is known about the prognostic significance of the time from surgery to first seizure relapse in predicting long-term outcome. METHODS: In a retrospective analysis of patients who reported at least one complex partial seizure...

objectives : there are two seriously limiting complications (agranulocytosis and seizure) in usage of clozapine as the major medication in treatment of schizophrenia. the present study was designed to investigate the degree of prevalence of seizure among patients under clozapine treatment. methods: the subjects were all the patients under clozapine treatment in shahid esma'ili psychiatric ...