Cleft is a congenital abnormal space or gap in the upper lip, alveolus, palate. This abnormality occurs between 5th and 10th weeks of pregnancy. Clefts are divided into cleft palate, as well lip palate caused by interaction individual genes with certain environmental factors. Mothers’ knowledge about risk factor may promote better health-related behavior their pregnancy increasing understanding...

UNLABELLED Cleft lip and/or palate (CL/P) represent the most common congenital anomalies of the face, corresponding to approximately 65% of all malformations of the craniofacial region. AIM to describe unusual clinical cases of non-syndromic CL/P (CL/PNS), diagnosed in a reference service in Minas Gerais, Brazil, and correlate these alterations with possible risk factors. MATERIALS AND METH...

In a search for genetic differences in susceptibility to cleft palate, congenic and recombinant inbred strains of mice were treated with 6-aminonicotinamide or control injections. Of six loci tested, only the chromosome segment marked by N-acetyl transferase was found to affect susceptibility to 6-aminonicotinamide-induced cleft palate. This chromosome segment is known to affect glucocorticoid-...

Background Dental fear is a prevalent phenomenon among children and adolescents globally. Aim To investigate dental 18-year-olds with cleft lip and/or palate (CLP) at their final follow-up clinic visit, to evaluate the association between OHRQoL. Design This cross-sectional study included cohort of CLP treated Oulu University Hospital Cleft Lip Palate Center, in northern Finland since 1995. A t...

Mesenchymal stem cells (MSCs) isolated from dental tissues have also been studied extensively recently due to their relatively easy availability. The researchers working on improving a method for regenerating alveolar bone in patients with cleft lip and palate utilizing mesenchymal human marrow (hBMSCs). A systematic literature review 2010 2022 was performed using PubMed, Medline, ScienceDirect...

OBJECTIVE In patients with cleft lip and palate, the aims of this study were to generate objective measures of different attributes of lip movement and to explore the utility of these objective measures by examining the association between examiners' subjective assessments with the objective measures. PATIENTS AND PARTICIPANTS Thirteen patients with unilateral cleft lip and palate with varyin...

Airway management in cleft lip and palate surgery Cleft lip and palate are the most common of the craniofacial anomalies, with an incidence of approximately 1 in 800 live births. Twenty-five percent of cases of cleft lip are bilateral, and 85 % of these are associated with cleft palate. In recent years there has been a move towards earlier surgical repair of both cleft lip and palate, with clef...

Outgrowth and fusion of the lateral and medial nasal processes and of the maxillary process of the first branchial arch are integral to lip and primary palate development. Wnt9b mutations are associated with cleft lip and cleft palate in mice; however, the cause of these defects remains unknown. Here, we report that Wnt9b(-/-) mice show significantly retarded outgrowth of the nasal and maxillar...

A child born with cleft lip and palate may experience difficulties while feeding. Obtaining a good seal of the oral cavity can be difficult due to the incomplete facial and palatal structures. Nasal regurgitation and choking are common in infants with cleft palate because of inability of the palate to separate the nasal and oral cavities. The case presented here is a 3-day-old neonate born with...

Author Disclosure Dr Abbott has disclosed no financial relationships relevant to this article. This commentary does not contain a discussion of an unapproved/ investigative use of a commercial product/ device. Editor’s Note: In the recently published article “Causal Attributions of Cleft Lip and Palate Across Cultures” (Cleft Palate Craniofac J. 2013;50[6]:655–661), the authors state that, acro...