Gutjahr, Welzl and Woeginger found polynomial-time algorithms for a number of digraph homomorphism problems. These algorithms are based on the X-enumeration, the Ck-extended X-enumeration and the X-graft construction. In this note we show how the last two methods can be combined to obtain new polynomial-time algorithms, which also work for list homomorphisms. In the process we are able to exten...

It is not uncommon for a rheumatologist to get a request for evaluating a patient with persistent elevation of serum creatine (phospho) kinase (CK) level (hyper-CK-emia) especially if this laboratory abnormality is persistent. We present a descriptive analysis of 16 consecutive adult patients seen with a condition called idiopathic benign hyper-CK-emia at a tertiary care Rheumatology Clinic in ...

Two new pyrene-cored covalent organic polymers (COPs), CK-COP-1 and CK-COP-2, were synthesized via the one-step polymerization of two thiophene-based isomers, 1,3,6,8-tetra(thiophene-2-yl) pyrene (L1 ) and 1,3,6,8-tetra(thiophene-3-yl) pyrene (L2 ). The resulting pyrene-cored COPs exhibit rather different surface areas of 54 m2 g-1 and 615 m2g-1 for CK-COP-1 and CK-COP-2, respectively. The CO2 ...

We compared the usefulness of four serum assays for classifying patients originally suspected of having an acute myocardial infarction. One of these is the long-used measurement of total creatine kinase (CK) activity. The other three are relatively new immunoassays: myoglobin by RIA, CK-BB by RIA, and CK-MB by immunoinhibition. When we evaluated test effectiveness with use of conventionally der...

BACKGROUND Serum creatine kinase-MB isoenzyme (CK-MB) is widely used as a marker of myocardial injury. We prepared recombinant human CK (r-hCK) MB isoenzyme and examined its potential for use as a control material for assay of CK-MB in serum. METHODS cDNAs encoding CK-M and CK-B subunits were inserted into the same plasmid vector, followed by transformation of Escherichia coli. The resulting ...

CK-MB values of >9 U/L and >4% CK-MB for potential MI. Because the modified calibration causes an “apparent” loss of CK-MB at the low end when compared with the KOdak calibration, we needed to determine whether the modified procedure retained good sensitivity. We analyzed a series of samples from two patients who displayed clinical evidence of MI 24 to 48 h before admission. The Hybritech proce...

BACKGROUND AND PURPOSE Creatine kinase-MB (CK-MB) increases in some patients with stroke, with no clear evidence of an acute coronary syndrome. Its elevations have been suggested to represent a biological marker for stroke-related myocardial injury. Troponin T has superior sensitivity and specificity to CK-MB in revealing minor myocardial injury. Therefore, we studied troponin T levels after st...

Background: For patients with an increased risk of developing myopathy with statin treatment, guidelines recommend to measure CK before and 6-12 weeks after initiating statin treatment. Further, in clinical trials of statins, the number of patients experiencing elevated creatine kinase (CK) serum activity is commonly reported as a safety parameter. Usually exceeding the upper limit of normal (U...

BACKGROUND Creatine kinase (CK)-MB elevation after percutaneous coronary intervention (PCI) has been associated with subsequent cardiac death. The patients at risk, the timing of risk, and potential treatment implications are uncertain. METHODS AND RESULTS Eight thousand, four hundred nine consecutive non- acute myocardial infarction patients with successful PCI and no emergency surgery or Q-...