Northern British Columbia was repeatedly covered by the Cordilleran Ice Sheet (CIS) during glacial periods. However, its mountainous terrain and remote location have thus far impeded our understanding of central sector ice sheet. The improved resolution remotely sensed data provides new opportunities to unravel history this inaccessible location. Here, we present a comprehensive map landforms f...

Background: Naturally extracted trans-(−)-kusunokinin from P. nigrum showed anticancer activities via binding and inhibition of CSF1R. However, the synthetic racemic mixtures trans-(−)- trans-(+)-kusunokinin (trans-(±)-kusunokinin) exhibited different effects on breast cancer cell lines. It was hypothesized that trans-(±)-kusunokinin bind to additional molecules, including AKR1B1. Previously, w...

A molecule isolated from the cerebrospinal fluid of sleep-deprived cats has been chemically characterized and identified as cis-9,10-octadecenoamide. Other fatty acid primary amides in addition to cis-9,10-octadecenoamide were identified as natural constituents of the cerebrospinal fluid of cat, rat, and human, indicating that these compounds compose a distinct family of brain lipids. Synthetic...

GENERAL ASPECTS OF HEPATOCYTE GROWTH FACTOR STRUCTURE AND FUNCTION 612 Biochemical and Structural Properties of Hepatocyte Growth Factor Protein 612 Pathways of Activation of Hepatocyte Growth Factor 612 Structure–Function Analysis of the Hepatocyte Growth Factor Molecule 613 Hepatocyte Growth Factor Gene Organization 613 Hepatocyte Growth Factor Gene and Its Transcriptional Control 614 Hepatoc...

New and simple protocols are described for the conversion of the enzymatically-derived and enantiomerically pure cis-1,2-dihydrocatechol (X = I) and its 6-methylated derivative into either antipodal form of compounds embodying the tricyclic frameworks of terpenoids . Key steps include intramolecular Diels-Alder (IMDA) and (in some cases) singlet or triplet-based photochemical processes.

<p>Este artigo aborda a diversidade e pluralidade de performances gênero, fazendo um contraponto à crença dominante que há apenas uma possibilidade performance, aquela baseada na cis-heteronormatividade, o torna as formas “diferentes” performar gênero invisíveis ou minorizadas. As pessoas performam identidades fora do padrão “normalidade” não têm reconhecido direito assumir suas da norma ...

This study assessed the effect of processing method on carotenoid profile oil from three varieties Nigerian palm fruits (Elaise guinensis). Specific Elaise guinensis, which are dura, pesifera and tenera were obtained National Institute for Oil Palm Research (NIFOR) in Edo state, Nigeria. The samples divided into two processed using different methods as commonly practiced south-eastern Nigeria, ...