background: the vascular response to recurrent tissue hypoxia and reperfusion following red blood cell sickling causes acute chest syndrome and chronic lung disease. the purpose of this study was to determine the pattern of chronic lung lesions and possible risk factors in sickle cell patients in lagos, nigeria.methods: from july 2012 to april 2013, pulmonary function test (pft) and chest-x-ray...

The aim of this study was to determine the relationship between C-reactive protein (CRP) levels and factors known to predict outcome in stable chronic obstructive pulmonary disease (COPD) patients. The following were studied in 130 stable COPD patients: spirometry, lung volume, arterial oxygen tension (P(a,O2)), dyspnoea, 6-min walk distance (6MWD), body mass index, fat-free mass index, BODE (b...

Acute exacerbations of chronic obstructive disease (AECOPD) are characterised by worsening dyspnoea that is variably prolonged. In this study, physiological changes during moderate AECOPD were examined and the factors associated with dyspnoea resolution over time were determined. In total, 20 patients experiencing an AECOPD were evaluated within 72 h of initial worsening of symptoms (day 0) wit...

1. Savi A, Gasparetto Maccari J, Frederico Tonietto T, Peçanha Antonio AC, Pinheiro de Oliveira R, de Mello Rieder M, Zignani EC, et al. Influence of FIO2 on PaCO2 during noninvasive ventilation in patients with COPD. Respir Care 2014; 59(3):383-387. 2. Lee J, Read J. Effect of oxygen breathing on distribution of pulmonary blood flow in chronic obstructive lung disease. Am Rev Respir Dis 1967;9...

BACKGROUND The World Health Organization has estimated that by 2030, chronic obstructive pulmonary disease will be the third leading cause of death worldwide. Most knowledge of chronic obstructive pulmonary disease is based on studies performed in Europe or North America and little is known about the prevalence, patient characteristics and change in lung function over time in patients in develo...

two main forms of copd (chronic obstructive pulmonary disease) refer to a group of lung diseases that block airflow and cause a huge degree of human suffering. a new method for identifying and estimating the severity of copd from three-dimensional (3-d) pulmonary x-ray ct images would be helpful for evaluation of treatment effects and early diagnosing is presented in this paper. this method has...

  Background: Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease, which reduces the lung function and causes respiratory symptoms over time, and it is primarily associated with shortness of breath, cough and sputum production. Roflumilast, which is a long-acting selective inhibitor, reduces the anti-inflammatory effect of the main symptoms of COPD. The aim of ...

introduction: arterial gas derangement could change urinary sodium excretion in chronic obstructive pulmonary disease (copd) patients.there are very few and conflicting data in regards to the measurement of fractional excretion of sodium in copd patients. the main aim of this study was to assess the relationship between renal fractional excretion of sodium(fena) with arterial blood gas and spir...