the patient had visceral leishmaniasis (kala-azar), successfully treated with 30 intramuscular injections of sodium stibogluconate (SSG). Polymerase chain reaction showed Leishmania donovani DNA in a buffy coat specimen. Post-kala-azar dermal leishmaniasis (PKDL) is a chronic skin rash usually seen in apparently cured kala-azar patients in East Africa and South Asia. In the Indian subcontinent,...

Methylsalicylate-containing rubefacients have been reported to cause salicylate poisoning after ingestion, topical application to abnormal skin, and inappropriate topical application to normal skin. Many over-the-counter products contain methylsalicylate. Topical salicylates rarely produce systemic toxicity when used appropriately; however, methylsaliclyate can be absorbed through intact skin. ...

This strongly alkaline chemical is widely used in industry as a feed stock for nitrogen-based chemicals such as fertilizers, plastics and explosives (ATSDR, 1990). Ammonia is also used as a refrigerant. The general public is exposed by off-gasing from cleaning solutions containing aqueous ammonia. Household ammonia solutions contain 5-10% ammonia in water while industrial strength can be up to ...

Toluene occurs naturally as a component of crude oil and is produced in petroleum refining and coke oven operations; toluene is a major aromatic constituent of gasoline (HSDB, 1999). It is used in household aerosols, nail polish, paints and paint thinners, lacquers, rust inhibitor, adhesives and solvent based cleaning agents. Toluene is also utilized in printing operations, leather tanning and ...

Sediment toxicity tests are valuable tools for assessing the potential effects of contaminated sediments in dredged material evaluations because they inherently address complexity (e.g., unknown contaminants, mixtures, bioavailability). Although there is a need to understand the chronic and sublethal impacts of contaminants, it is common to conduct only short-term lethality tests in evaluations...

Objective: To investigate Acute, Sub-acute dermal toxicity, Mucus membrane irritation activity of Anuradha Oil’s (AO and AO11) – An herbal formulation having wound healing potential. Methods: The formulations were derived from Curcuma longa Linn and Glycyrrhiza glabra Linn rhizhomes, Hamiltonia suaveolens Roxb bark, Typha angustifolia Linn flowers, Azadirachta indica A. Juss leaves without/with...