UNLABELLED Methicillin-resistant Staphylococcus aureus (MRSA) has become a leading cause of colonization and infection in both acute and chronic soft-tissue wounds. OBJECTIVE Our objective is to define this current epidemic problem caused by both community-acquired MRSA (CA-MRSA) and hospital-acquired MRSA (HA-MRSA), focusing on the similarities and differences between these 2 isolates as wel...

Liver-induced systemic immune tolerance that occurs during chronic hepadnavirus infection is the biggest obstacle for effective viral clearance. Immunotherapeutic reversal of this tolerance is a promising strategy in the clinic but remains to be explored. In this study, using a hepatitis B virus (HBV)-carrier mouse model, we report that IL-12-based vaccination therapy can efficiently reverse sy...

BACKGROUND Hepatitis B virus (HBV) infection is endemic in China; perinatal transmission is the main source of chronic HBV infection. Simultaneous administration of hepatitis B immune globulin (HBIG) and hepatitis B vaccine is highly effective to prevent perinatal transmission of HBV; however, the effectiveness also depends on full adherence to the recommended protocols in daily practice. In th...

Aim. To investigate the relationship between hepatitis B e antigen seroconversion and the function of dendritic cells (DC) in patients with hepatitis B virus. Methods. The peripheral blood mononuclear cells (PBMC) from 21 chronic HBV patients in immune tolerance state, 23 patients in inactive HBsAg carrier state, and 10 healthy HBV-naive blood donors were incubated and induced into DC in presen...

background and objectives rheumatoid arthritis (ra) is a chronic inflammatory disease which is characterized by joint swelling, and synovial inflammation. c reactive protein (crp) and ceruloplasmin (cp) are identified as important biomarkers of ra and various inflammatory diseases. curcumin, a widely used yellow color spice is the most active component of curcuma longa l (turmeric). curcumin co...

objective(s): researchers have intended to reformulate drugs so that they may be more safely used in human body. polymer science and nanotechnology have great roles in this field. the aim of this paper is to introduce an efficient drug delivery vehicle which can perform both targeted and controlled antibiotic release using magnetic nanoparticles grafted ph-responsive polymer.  methods: fe3o4 na...

a study was carried out to determine whether naturally-occurring weeds and other cultivated plants in tomato growing regions could act as symptomless reservoirs of infection to fusarium oxysporum f. sp. lycopersici. a numher of f. oxysporum isolates from weeds and oubergines were used in this investigation. a susceptible tomato cultivar was used for comparison. the plants were artificially ...

We have examined the amino acid transport in B cell chronic lymphocytic leukemia and compared it with the amino acid transport in isolated B lymphocytes from human blood and tonsils. L-system transport was measured with 2-amino-2-carboxy-bicyclo (2,2,1)-heptane, which is a synthetic amino acid whose transport is limited to the L-system. Amino acid uptake was subjected to a multicomponent analys...

background and objectives : in iran, anaplasmosis is normally diagnosed with traditional giemsa staining method. this is not applicable for identification of the carrier animals. the aim of this study was to compare the detection of anaplasma marginale in two different numbers of microscopic fields (50 and 100) using conventional giemsa staining method compared with the pcr-rflp technique. mate...